Senior Safety Scientist I

Role: Senior Safety Scientist supporting pharmacovigilance across Revolution Medicines' oncology portfolio, including early and late-phase clinical trials of RAS(ON) inhibitors for mutations in the RAS pathway. Responsibilities: conduct proactive safety surveillance, review and author safety documents (protocols, IBs, ICFs, DSURs), perform medical review of ICSRs, identify safety signals, contribute to risk management, and support regulatory submissions and safety communications. Maintain safety awareness of product profiles, produce safety summaries, and collaborate with cross-functional teams, CROs, and external stakeholders. Requirements: postgraduate qualification (e.g., MD, PharmD, PhD, MSc), 3+ years in drug development with at least 1 year in drug safety, strong knowledge of pharmacovigilance (GVP, GCP), safety operations, and risk management. Preferred: experience in oncology, biologics or small molecules, early/late clinical development stages, and regulatory filings. HighValue: oncology (RAS pathway), clinical safety, pharmacovigilance, safety data review, signal detection, regulatory support, GxP compliance. WorkSetup: based in Redwood City, CA, with competitive salary range $164K-$205K, and potential for remote or hybrid work.