Senior Research Associate, Molecular Biology and Sequencing
Flagship Pioneering
September 11, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Other
Role: Senior Research Associate in Molecular Biology & Sequencing, responsible for developing and executing next-generation sequencing (NGS) and high-throughput cloning workflows to support a biotech platform focused on biomolecule synthesis. Core responsibilities include performing NGS library prep and operation on Illumina MiSeq and NextSeq platforms, executing high-throughput cloning methods (Gibson, Golden Gate), assembling and QC of large pooled variant libraries, and managing sample tracking and data documentation. The role involves collaborating with enzyme engineering, chemical biology, and computational teams to convert sequencing data into actionable insights, and optimizing protocols for throughput and quality. Qualifications: B.S. with 5+ years or M.S. with 3+ years of relevant molecular biology experience; extensive hands-on proficiency with Illumina platforms, cloning workflows, and library QC; strong organizational skills; meticulous sample management and documentation. Preferred qualifications include experience in nucleic acid enzyme characterization, bioinformatics analysis (command line, Python, R), high-throughput enzyme assays, and working with automation tools and data management systems. High-value specifics: role supports a pioneering biotech platform targeting innovative molecule synthesis, with emphasis on assay development, molecular biology, and data interpretation within a fast-paced startup environment. Location: Not specified; likely onsite or hybrid based on lab work and collaboration needs.