Senior Research Associate, Analytical Development

Role Summary

Senior Research Associate, Analytical Development located in Center City, Philadelphia. Reporting to the Associate Principal Scientist, Analytical Development, this role supports activities of routine analytical testing and method qualification for the rese-cel clinical program. The ideal candidate is a biology-trained scientist with QC testing experience for lentiviral vectors and CAR-T cells and method qualification.

Responsibilities

• Perform quality control testing to evaluate lentiviral vectors, CAR-T cells and stability samples generated by internal groups and external partners.
• Assist in developing analytical methods for the characterization and release of lentiviral vectors and CAR-T cells.
• Identify and implement opportunities for analytical method improvement and participate in optimization of existing analytical methods to enhance sensitivity and efficiency.
• Perform method qualification studies in accordance with regulatory guidelines.
• Perform general lab and equipment maintenance duties.
• Participate in technical troubleshooting and problem investigation.
• Prepare, evaluate, and present data internally to cross functional teams.
• Prepare detailed and accurate documentation of experimental procedures, results, and conclusions.
• Stay current with advances in analytical techniques and industry trends.
• Other related duties, as assigned.

Qualifications

• Required: Bachelor’s or master’s degree in biology or closely related discipline, with 1–3 years of experience.
• Required: Proficient in aseptic technique for cell culture and cell-based assays.
• Required: Experience in analytic techniques, including flow cytometry, qPCR/dPCR, or ELISA, etc.
• Required: Flexible to support various analytical activities and to learn new techniques outside of existing field of expertise.
• Preferred: Experience with quality control programs for lentiviral vector and CAR-T product.
• Required: Ability to work collaboratively in a fast-paced environment.
• Required: Highly organized with strong written and verbal communication skills.
• Required: Strong laboratory documentation practice with high scientific integrity.
• Required: Strong team orientation and passion for continuous self-development.
• Preferred: Experience in the biotech industry or in a startup industrial setting.