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Role Summary
Senior Research Associate
Responsibilities
Contribute to the development of SOPs and assay workflows for pre-clinical and clinical assays.
Contribute to data processing and preparation for client presentation.
Perform basic and advanced cell culture to characterize growth and survival under treatment by client test agents through the use of 2-D and 3-D cell-based assays.
Lead small scale projects that are specific to cell- banking or operations.
Contribute to the development and execution of 3-D co-culture assays including primary, PDX, and immune cells.
Efficiently plan and execute cell line scheduling for in vivo studies.
Perform molecular biology endpoints including qRT-PCR, ELISA, Western Blot, and Luminex.
Responsible for operating and assisting in development of high throughput automated laboratory systems including liquid handlers, dosing units, plate readers, and high content imaging equipment.
Documentation and maintenance of laboratory and supply inventory by working with facilities and procurement team.
Communicate the scientific outcomes of experiments/projects between teams in a clear and detailed manner.
Contribute to the culture of the ex vivo group by demonstrating high performance, sporting accountability and fostering collaboration and teamwork.
Other duties may be assigned verbally at any time.
Qualifications
Experience and well versed in cell culture and cell-based assays.
Proficiency handling primary cells, tumor tissue, and various blood products including serum/plasma, whole blood, and PBMCs.
Proficiency with one or more additional molecular biology techniques including qRT-PCR, ELISA, Western Blot, and Luminex.
Experience with flow cytometry and sequencing is preferred but not required.
Experience managing small-scale projects and maintaining strong communication skills are required.
Demonstrated ability to work effectively and productively in a team-oriented environment while maintaining a strong sense of integrity and confidentiality.
Creative problem-solving skills and the ability to exercise sound and accurate judgment in making timely decisions.
Strong planning, organizational, computer, written and verbal communication skills.
Demonstrated accountability, initiative, and responsibility for own work.
Ability to observe safety and security procedures.
Ability to assist with other tasks/duties as needed in a small company environment.
Education
BS or MS degree with 2-4 years of relevant experience required. Preferred field of study in biology, or related sciences.
Laboratory based experience and knowledge of aseptic technique/cell culture is required.
Additional Requirements
Must be able to sit and use hands to finger, handle and feel.
Must be able to lift and move packages weighing up to 50 pounds.
Some activities require repetitive motion and reaching, pulling or pushing.
In carrying out the duties of the job there will be frequent exposure to fumes and chemical hazards.
Duties performed routinely require exposure to blood, body fluid and tissue.