Senior Project Manager, Clinical Operations
Maze Therapeutics
August 14, 2026
Remote friendly (South San Francisco, CA)
United States
Operations
Responsibilities:
- Partner with Clinical Operations Study Leads and Oversight Directors to manage project management activities across multiple Phase 1/clinical pharmacology, Phase 2, and Phase 3 studies; align timelines, milestones, dependencies, and deliverables.
- Create and maintain integrated project plans, timelines, risk registers, and action trackers; monitor milestones, dependencies, risks, and deliverables; escalate and drive timely issue resolution.
- Coordinate cross-functional execution with Clinical Science, Biometrics, Data Management, Regulatory Affairs, Clinical Supply, Quality Assurance, Finance, and others.
- Lead governance: coordinate and facilitate Study Execution Team (SET) meetings, develop agendas, document decisions/actions, and run operational reviews and planning sessions.
- Oversee strategic initiatives (eTMF implementation/governance, AI initiatives, CDx workflows, SOP revisions, inspection readiness, CTMS/eTMF/dashboards systems implementations, process improvement/change).
- Develop standardized tools/templates, KPIs, dashboards/status reports, and support onboarding/training and continuous improvement.
Qualifications (required):
- Bachelor’s degree in Life Sciences (or related).
- 6–8+ years Clinical Project Management, or 8+ years Clinical Operations (with 6+ years Clinical Project Management in biotech).
- Proven experience managing complex cross-functional projects across multiple clinical studies/programs.
- Strong understanding of clinical trial operations (early-phase, clinical pharmacology, Phase 2, Phase 3).
Skills/Preferred:
- Experience facilitating governance meetings, managing timelines, and driving action items.
- Preferred experience with operational improvement/change management.
- Preferred: dashboards/exec reporting; tools (Smartsheet/Microsoft Project) and Microsoft Office; GCP environment and systems (CTMS, eTMF, EDC).
Benefits/Compensation (as stated):
- Expected salary range (SF Bay Area): $181,000–$221,000; eligible for annual performance bonus.
- Benefits include medical/dental/vision, mental health offerings, equity incentive plan, 401(k) match, and generous PTO/holidays.
- Partner with Clinical Operations Study Leads and Oversight Directors to manage project management activities across multiple Phase 1/clinical pharmacology, Phase 2, and Phase 3 studies; align timelines, milestones, dependencies, and deliverables.
- Create and maintain integrated project plans, timelines, risk registers, and action trackers; monitor milestones, dependencies, risks, and deliverables; escalate and drive timely issue resolution.
- Coordinate cross-functional execution with Clinical Science, Biometrics, Data Management, Regulatory Affairs, Clinical Supply, Quality Assurance, Finance, and others.
- Lead governance: coordinate and facilitate Study Execution Team (SET) meetings, develop agendas, document decisions/actions, and run operational reviews and planning sessions.
- Oversee strategic initiatives (eTMF implementation/governance, AI initiatives, CDx workflows, SOP revisions, inspection readiness, CTMS/eTMF/dashboards systems implementations, process improvement/change).
- Develop standardized tools/templates, KPIs, dashboards/status reports, and support onboarding/training and continuous improvement.
Qualifications (required):
- Bachelor’s degree in Life Sciences (or related).
- 6–8+ years Clinical Project Management, or 8+ years Clinical Operations (with 6+ years Clinical Project Management in biotech).
- Proven experience managing complex cross-functional projects across multiple clinical studies/programs.
- Strong understanding of clinical trial operations (early-phase, clinical pharmacology, Phase 2, Phase 3).
Skills/Preferred:
- Experience facilitating governance meetings, managing timelines, and driving action items.
- Preferred experience with operational improvement/change management.
- Preferred: dashboards/exec reporting; tools (Smartsheet/Microsoft Project) and Microsoft Office; GCP environment and systems (CTMS, eTMF, EDC).
Benefits/Compensation (as stated):
- Expected salary range (SF Bay Area): $181,000–$221,000; eligible for annual performance bonus.
- Benefits include medical/dental/vision, mental health offerings, equity incentive plan, 401(k) match, and generous PTO/holidays.