Senior Principal Scientist (Senior Director), Clinical Research, ADC
Merck
12 days ago
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Role Responsibilities:
- Plan and direct clinical research activities for new medicines in the Oncology therapeutic area (including study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication).
- Evaluate pre-clinical/translational work to generate early clinical development plans and IND applications.
- Develop clinical development strategies.
- Plan clinical trials (design and operational planning).
- Provide medical oversight and overall conduct of clinical trials, including dose optimization.
- Analyze/summarize clinical findings to support safety/efficacy decisions, new drug applications, clinical study reports, and publication.
- Participate in internal and joint internal/external project teams.
- Work with tumor teams (PDTs) to transition investigational drugs to registrational studies.
- Support business development assessments of external opportunities.
May:
- Engage cross-functionally to support study execution; collaborate with experts in commercialization, regulatory affairs, statistics, and manufacturing.
- Provide expert scientific opinions internally/externally.
Education:
- M.D. or M.D./Ph.D.
Required Experience/Skills:
- Industry or senior faculty (academia) experience.
- Minimum 3 years clinical medicine experience.
- Minimum 3 years industry drug development or biomedical research (academia).
- Demonstrated success overseeing clinical studies/protocols; scientific scholarship.
- Strong interpersonal/team skills.
Preferred Experience/Skills:
- Board Certified or Eligible in Oncology (or related).
- Prior clinical research and publication.
Required Skills:
Antibody Drug Conjugates (ADC), Clinical Development, Clinical Documentation/Reporting, Clinical Trial Development/Trials, Drug Development, Ethical Standards, Oncology, Pharmaceutical Development, Regulatory Compliance/Reporting, Strategic Planning.
Benefits/Compensation:
- Annual bonus and long-term incentive (if applicable).
- Comprehensive benefits including medical/dental/vision, retirement (401(k)), paid holidays, vacation, and compassionate/sick days.
Application Instructions:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub). Apply by the deadline stated on the posting (Job posting end date: 06/11/2026).
- Plan and direct clinical research activities for new medicines in the Oncology therapeutic area (including study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication).
- Evaluate pre-clinical/translational work to generate early clinical development plans and IND applications.
- Develop clinical development strategies.
- Plan clinical trials (design and operational planning).
- Provide medical oversight and overall conduct of clinical trials, including dose optimization.
- Analyze/summarize clinical findings to support safety/efficacy decisions, new drug applications, clinical study reports, and publication.
- Participate in internal and joint internal/external project teams.
- Work with tumor teams (PDTs) to transition investigational drugs to registrational studies.
- Support business development assessments of external opportunities.
May:
- Engage cross-functionally to support study execution; collaborate with experts in commercialization, regulatory affairs, statistics, and manufacturing.
- Provide expert scientific opinions internally/externally.
Education:
- M.D. or M.D./Ph.D.
Required Experience/Skills:
- Industry or senior faculty (academia) experience.
- Minimum 3 years clinical medicine experience.
- Minimum 3 years industry drug development or biomedical research (academia).
- Demonstrated success overseeing clinical studies/protocols; scientific scholarship.
- Strong interpersonal/team skills.
Preferred Experience/Skills:
- Board Certified or Eligible in Oncology (or related).
- Prior clinical research and publication.
Required Skills:
Antibody Drug Conjugates (ADC), Clinical Development, Clinical Documentation/Reporting, Clinical Trial Development/Trials, Drug Development, Ethical Standards, Oncology, Pharmaceutical Development, Regulatory Compliance/Reporting, Strategic Planning.
Benefits/Compensation:
- Annual bonus and long-term incentive (if applicable).
- Comprehensive benefits including medical/dental/vision, retirement (401(k)), paid holidays, vacation, and compassionate/sick days.
Application Instructions:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub). Apply by the deadline stated on the posting (Job posting end date: 06/11/2026).