Senior Principal Scientist, Preclinical Safety & Translational Sciences-Translational Pharmacokinetics/Pharmacodynamics

Role: Senior Principal Scientist in Preclinical Safety & Translational Sciences, specializing in Pharmacokinetics & Pharmacodynamics, focusing on modeling to inform early drug development decisions. Responsibilities: apply PK/PD modeling, guide modeling strategies, contribute to project team decision-making from discovery to early clinical phases, and support model-based analyses like physiologically-based PK and systems pharmacology. Requirements: PhD in Pharmacology, Engineering, Mathematics, Physics, or related field with 6+ years (PhD) or 8+ years (Master's) industry experience; strong background in PK/PD principles and modeling; peer-reviewed publications preferred. HighValue: expertise in PK/PD modeling, translational sciences, early drug development, contribution to project strategies; familiarity with quantitative modeling tools. WorkSetup: based in Spring House, PA or La Jolla, CA, with potential for hybrid work.