Senior Principal Scientist, Cardiovascular, Translational Development
Bristol Myers Squibb
June 24, 2026
Remote friendly (Princeton, NJ)
United States
Clinical Research and Development
Position Summary
Senior Principal Scientist, Cardiovascular, Translational Development (Translational Development within Global Research; leads late-stage clinical/pharmacological/translational R&D and late-stage portfolio support).
Key Responsibilities
- Design and implement program-specific development biomarker/translational plans.
- Support creation of clinical protocols, SAPs, SOWs, and lab manuals; interface with CROs for service execution with Biospecimen Operations/Procurement.
- Select assays/vendors for clinical biomarkers; manage outsourcing of biomarker assay development/validation.
- Manage biomarker data delivery/analysis timelines with internal functions and CROs.
- Prepare and deliver translational/biomarker presentations; maintain publication timelines with Medical Communications/Publications.
- Stay current on scientific/technical literature; act as subject-matter expert on asset/disease biology.
- Address nonclinical translational questions with TM lab scientists/academic TLs.
- Lead/participate in post-hoc biomarker analysis and publication; support regulatory submissions/interactions.
- Support PDx biomarker assay development with precision medicine group.
Qualifications & Experience
- PhD with 5–8+ years translational medicine/clinical biomarker experience; 5+ years supporting early- and/or late-stage clinical programs in biotech/pharma.
- Recognized expertise in cardiovascular (or related) translational biomarkers; experience across drug development and clinical trial initiation/conduct/completion.
- CRO/thought-leader experience managing projects, timelines, deliverables.
- Scientific/project leadership (cross-functional, mentoring, risk/contingency planning).
- Experience with dataset mining/interpretation with bioinformaticians.
- Strong presentation/communication to leadership and governance; organizational accuracy for multiple fast-paced projects.
Benefits (explicitly listed)
- Health coverage (medical/pharmacy/dental/vision).
- Wellbeing programs (incl. EAP); financial protection (401(k), disability, life/accident/supplemental insurance).
- Paid time off, flexible time off/paid vacation options, national holidays; additional eligible time off (e.g., sick time, volunteer days, leaves, global shutdown).
Application Instructions
- If the role doesn’t fully match your resume, apply anyway.
Senior Principal Scientist, Cardiovascular, Translational Development (Translational Development within Global Research; leads late-stage clinical/pharmacological/translational R&D and late-stage portfolio support).
Key Responsibilities
- Design and implement program-specific development biomarker/translational plans.
- Support creation of clinical protocols, SAPs, SOWs, and lab manuals; interface with CROs for service execution with Biospecimen Operations/Procurement.
- Select assays/vendors for clinical biomarkers; manage outsourcing of biomarker assay development/validation.
- Manage biomarker data delivery/analysis timelines with internal functions and CROs.
- Prepare and deliver translational/biomarker presentations; maintain publication timelines with Medical Communications/Publications.
- Stay current on scientific/technical literature; act as subject-matter expert on asset/disease biology.
- Address nonclinical translational questions with TM lab scientists/academic TLs.
- Lead/participate in post-hoc biomarker analysis and publication; support regulatory submissions/interactions.
- Support PDx biomarker assay development with precision medicine group.
Qualifications & Experience
- PhD with 5–8+ years translational medicine/clinical biomarker experience; 5+ years supporting early- and/or late-stage clinical programs in biotech/pharma.
- Recognized expertise in cardiovascular (or related) translational biomarkers; experience across drug development and clinical trial initiation/conduct/completion.
- CRO/thought-leader experience managing projects, timelines, deliverables.
- Scientific/project leadership (cross-functional, mentoring, risk/contingency planning).
- Experience with dataset mining/interpretation with bioinformaticians.
- Strong presentation/communication to leadership and governance; organizational accuracy for multiple fast-paced projects.
Benefits (explicitly listed)
- Health coverage (medical/pharmacy/dental/vision).
- Wellbeing programs (incl. EAP); financial protection (401(k), disability, life/accident/supplemental insurance).
- Paid time off, flexible time off/paid vacation options, national holidays; additional eligible time off (e.g., sick time, volunteer days, leaves, global shutdown).
Application Instructions
- If the role doesn’t fully match your resume, apply anyway.