Senior Medical Director, Rheumatology

Role Summary

Senior Medical Director in Clinical Development responsible for the full scope of rheumatology and autoimmune clinical drug development activities from discovery through Phase 3, including leadership of one or more studies and collaboration with cross-functional asset teams to advance clinical programs and asset strategy.

Responsibilities

• Serve as the physician lead for LUMUS, a 388-patient Phase 2b trial evaluating multiple doses of ESK-001 in adults with moderately to severely active, autoantibody-positive SLE.
• Provide leadership of in-stream data reviews and reconciliation efforts.
• Authorship of clinical portions of key study documents, such as Protocol Amendments and Regulatory Submissions.
• Provide oversight of the LUMUS medical monitor.
• Participates in external scientific engagement, including peer-to-peer interactions with MDs.
• Represent the interests of Alumis as a leader, supporting corporate initiatives across rheumatology.
• Coach, manage, inspire, and support team members to achieve goals by leveraging a focused and collaborative mindset.
• Maintain the highest levels of integrity and standards for scientific inquiry in drug development.

Qualifications

• MD (or ex-US equivalent) with board certification in Rheumatology.
• 5+ years of clinical development experience; lupus clinical trials background is desired.
• Proven leadership skills, with experience managing people within a pharmaceutical company or clinical/academic environment.
• Ability to assess, understand, and communicate expanding medical and scientific information.
• Strong track record of strategic, organizational, and executional skills to support project planning across multiple activities, with ability to prioritize multiple projects.
• Organized approach with attention to detail and ability to meet timelines in a fast-paced environment.
• Ability to work across diverse teams in a matrixed structure as a leader and team member.
• Strong interpersonal, influencing, presentation, and communications skills (written and verbal).
• Ability to work autonomously and with a high level of independence.
• Willingness to travel to South San Francisco HQ for one week per month.

Education

• MD (or equivalent) with board certification in Rheumatology.

Additional Requirements

• Location: South San Francisco, CA; onsite Tuesday-Thursday with remote option requiring monthly onsite presence.