Senior Medical Director, Portfolio Strategy, Medical Evidence Generation

Role Summary

Senior Medical Director of Portfolio Strategy, Medical Evidence Generation will shape and execute a cohesive scientific and medical strategy across the franchise portfolio. This role drives cross-functional and cross-therapeutic area alignment in evidence generation to inform strategic decisions and improve patient outcomes. Partner with R&D, Medical, Commercial, and Market Access, and engage with external stakeholders including key opinion leaders.

Responsibilities

• Portfolio Medical Strategy & Evidence Generation (40%)
  • Design and implement a unified, portfolio-wide Integrated Evidence Generation Plan (iEGP) aligned with Franchise strategies and Lifecycle Management priorities.
  • Lead cross-TA innovation in evidence generation (including real-world evidence) across R&D, Medical Affairs, Commercial, and Market Access.
  • Identify data gaps and opportunities, offering strategic recommendations for optimal investment and impact-driven decisions.
  • Enhance external engagement and data-generation partnerships; pilot AI-enabled RWE platforms.
  • Monitor advancements and competitive activity to reinforce franchise leadership in medical evidence generation.
  • Collaborate with TAs, markets, and external partners to establish a robust RWE framework with timely, high-quality results.
• Cross-Functional & Regional Alignment (30%)
  • Ensure consistent integration of the iEGP across therapeutic areas, functions, and regions to drive alignment and impact.
  • Work with program management, therapeutic area, country, and regional medical teams to optimize the iEGP with measurable medical and patient outcomes.
• Impact Assessment & Execution Excellence (20%)
  • Define and implement KPIs to evaluate iEGP impact and data dissemination across therapeutic areas.
  • Analyze market insights to refine and innovate the iEGP; maintain competitiveness and alignment with objectives.
  • Standardize planning processes of iEGP across Global Medical Affairs ‚Äì Alliance Immunology for consistency and excellence.
• Portfolio & Stakeholder Engagement (10%)
  • Oversee stakeholder engagement strategies across indications, including KOL lists and segmentation.
  • Represent the franchise to external KOLs and stakeholders at conferences and events.
  • Support medical thought leadership in immunology and related areas with scientific discussions and engagement frameworks.

Qualifications

• Advanced scientific degree (MD, PhD, PharmD) required. Immunology experience preferred.
• 10+ years of cross-TA experience; portfolio management and strategic planning across TAs required.
• Deep knowledge in dermatology, respiratory, rhinology, GI, and/or immunology.
• Strategic planning expertise from global management consulting is a strong asset.
• Expertise in real-world evidence generation, lifecycle management, and medical impact measurement.
• Proven leadership in medical affairs, RWE, data generation, and stakeholder engagement.
• Strategic mindset to develop and execute cross-TA strategy; experience across multiple TAs.
• Strong ability to work in a matrixed global environment with cross-functional and cross-regional teams.
• Excellent stakeholder management skills; experience with KOL engagement and external scientific communication.

Skills

• Evidence generation strategy
• Real-world evidence (RWE) and data analytics
• Lifecycle management
• Strategic planning and portfolio management
• Stakeholder engagement and KOL management
• Cross-functional leadership in a global matrix
• Scientific storytelling and communications

Education

• Advanced scientific degree (MD, PhD, PharmD)