Senior Medical Director, Oncology Clinical Development - Lung

In This Role You Will:
- Serve as a senior physician leader within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretation
- Provide guidance on medical monitoring and safety oversight across studies
- Interpret complex clinical and safety data to inform programme-level decisions led by the CDL
- Partner with the Senior Scientist and cross-functional teams to integrate medical considerations across study execution and programme delivery
- Provide senior medical input into protocol development and study design (clinical relevance and patient-centred design)
- Serve as a senior member of the Clinical Matrix Team (CMT), influencing study-level and programme-level decision-making
- Engage with investigators, Key External Experts (KEEs), and scientific leaders; represent the programme at advisory boards, steering committees, and scientific forums
- Provide medical guidance and mentorship to Medical Directors within the programme

Detailed Responsibilities:
- Medical Monitoring and Safety Oversight: ensure consistency in approach/patient safety/protocol adherence; guide safety data interpretation with pharmacovigilance; contribute to safety review forums (SRT, IDMC); align medical monitoring approaches with regulatory/organisational standards
- Study Design and Execution: provide protocol input; guide complex/high-risk/multi-study design and implementation; resolve complex medical questions during conduct
- Data Interpretation and Scientific Contribution: integrate complex data to inform safety/efficacy/patient-impact insights; support CDL benefit–risk assessment; guide scientific communications; apply disease biology and treatment-paradigm knowledge
- Regulatory and External Engagement: support Health Authority interactions; represent programme externally; engage KEEs/collaborators; lead/contribute to business-development diligence
- Cross-Functional Collaboration/CMT: drive cross-functional alignment; contribute to evidence planning and Medical Affairs; lead Oncology Clinical Development initiatives
- People Leadership: oversee/mentor Medical Directors; coach capability building

Basic Qualifications:
- Medical degree and advanced specialty training/fellowship (oncology, haematology, or related)
- Oncology clinical development experience across multiple studies/programmes
- Medical monitoring, safety evaluation, and clinical data interpretation experience
- Understanding of clinical development processes, GCP, ICH guidelines, and global regulatory frameworks
- Experience in cross-functional matrix teams and programme-level decisions

Preferred Qualifications:
- Strong scientific communication and stakeholder engagement
- Oncology clinical development across Phase I–III
- Experience in regulatory interactions (e.g., IND, scientific advice, NDA/MAA)
- Publications/congress presentations; deep oncology disease biology knowledge; mentoring/oversight; diligence for business development

Skills:
Clinical Data Interpretation, Clinical Pharmacology, Clinical Trial Designs, Clinical Trials Monitoring, Drug Development, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations, Strategic Direction

Benefits/Compensation (if applicable in posting): US base salary range $284,250–$473,750 plus annual bonus and eligibility for share-based long-term incentive; benefits include health/insurance, retirement, paid holidays/vacation, paid caregiver/parental and medical leave. Poland gross base salary range PLN 593,250–PLN 988,750 (plus potential bonus and long-term incentive).

Application/On-site requirement: On-site presence minimum two days per week at Switzerland (Zug), Poland (Warsaw), UK (Stevenage or London HQ), or US (PA or MA) sites.