Senior Medical Director, Integrated Evidence Generation – Nephrology

Role Summary

The Sr. Medical Director, Integrated Evidence Generation – Nephrology will serve as the strategic architect of Travere’s Medical Affairs–led evidence infrastructure. This role defines and executes a multi-year integrated evidence strategy spanning post-approval interventional and non-interventional studies, investigator-sponsored research, collaborative research, real-world evidence, and lifecycle management. The role chairs the Evidence Generation Committee and acts as the senior medical authority on post-approval and lifecycle evidence, partnering cross-functionally to strengthen scientific credibility and long-term asset value. Location: San Diego, USA – Remote.

Responsibilities

• Integrated Evidence & Lifecycle Strategy
  • Define and lead a 3–5-year integrated evidence roadmap aligned to lifecycle and access priorities
  • Serve as Medical Affairs evidence lead for lifecycle management planning and execution
  • Identify and address evidence gaps supporting label expansion, new subpopulations, combination strategies, durability, and long-term safety
  • Ensure evidence strategy strengthens regulatory positioning and lifecycle business cases
  • Partner with Clinical Development and Regulatory to align post-approval evidence with future development plans
• Evidence Governance & Investment Oversight
  • Chair and govern the cross-functional Evidence Generation Committee
  • Establish clear prioritization criteria and portfolio governance processes
  • Oversee investment decisions across MA-led studies, ISR, collaborative research, and RWE
  • Ensure evidence investments are strategically aligned to lifecycle objectives
  • Provide executive-level updates to TA and GMA leadership
• ISR & Collaborative Research Strategy
  • Establish and lead ISR governance framework within the TA
  • Define scientific prioritization aligned to strategic data gaps
  • Curate an ISR and collaborative research portfolio that advances guideline positioning, access strategy, and future development opportunities
  • Oversee partnerships with academic institutions, research networks, and Centers of Excellence
  • Monitor scientific impact and return on investment
• Real-World Evidence (RWE) Leadership
  • Co-lead RWE strategy in partnership with Patient Access/HEOR
  • Align RWE initiatives with lifecycle, guideline, and access priorities
  • Identify and evaluate strategic data partnerships and registries
  • Ensure RWE outputs inform clinical practice insights, compendia engagement, and value demonstration
• Build & Scale Medical Affairs–Led Research Capability
  • Establish and expand Travere’s Medical Affairs–led research capability
  • Develop scalable frameworks to support post-approval interventional, non-interventional, and implementation science studies
  • Identify opportunities where MA-led research complements Clinical Development and strengthens lifecycle strategy
  • Operationalize compliant, fit-for-purpose execution models appropriate for Travere
• External Scientific Leadership & Therapeutic Area Partnership
  • Represent Travere in strategic society research initiatives and academic collaborations
  • Engage key opinion leaders, steering committees, and research consortia
  • Serve as internal authority on evolving evidence methodologies and standards
  • Contribute to cross-functional planning, advisory boards, and broader Medical Affairs priorities based on expertise and organizational needs
  • Collaborate with field medical teams to execute external expert interactions, evidence-generation activities, and training programs aligned with emerging evidence and medical strategies

Qualifications

• Advanced scientific degree (MD, PharmD, PhD)
• 8+ years of experience in Medical Affairs, clinical research, evidence generation, or other relevant experience
• Deep expertise in interventional and non-interventional study design, RWE methodologies, ISR governance, post-approval and lifecycle evidence strategy
• Experience contributing to or leading lifecycle management planning
• Demonstrated ability to influence executive decision-making
• Proven ability to operate in a lean, high-accountability biotech environment

Skills

• Demonstrated ability to influence important customers, challenge common perceptions, and implement medical affairs tools to improve patient care and outcomes
• Exemplary verbal and written communication skills, including formal presentation skills, and well-developed interpersonal skills
• Strong organizational skills with the ability to prioritize and execute against key objectives and deliverables, on time and within budget
• Demonstrates the highest ethical standards with strong knowledge of and adherence to applicable regulatory, legal, and compliance requirements
• Highly adaptable and resourceful, with the ability to prioritize, manage complexity, and collaborate effectively in a fast-paced, cross-functional environment

Additional Requirements

• Travel up to 40% (ASN, ERA-EDTA, NKF, KOL symposiums, etc.) and on-site presence in San Diego; some evenings and weekend availability may be required
• On-site presence in San Diego; no role is expected to be 100% remote