Senior Medical Director, Clinical Development Rheumatology
Zenas BioPharma
June 24, 2026
Remote friendly (Waltham, MA)
United States
Clinical Research and Development
Position Summary
The Senior Medical Director, Clinical Development Rheumatology will lead the clinical development plan for one or more assets and oversee medical and safety responsibilities for global clinical trials across all phases. Collaborates with Clinical Operations, Clinical Pharmacology, Medical and Scientific Affairs, and externally with KOLs/Investigators, Regulatory Authorities, and Patient Advocacy Groups.
Key Responsibilities
- Lead clinical development plan and overall clinical strategy for multiple global programs.
- Identify unmet medical needs in autoimmune disorders.
- Oversee clinical study design, including authoring study synopses/protocols; collaborating with biostats on the SAP; providing medical monitoring and safety oversight (GCP); interpreting clinical data and authoring CSRs.
- Develop relationships with Investigators, research sites, and KOLs to design trials addressing key medical questions.
- Support publication strategy by preparing/submitting clinical findings to scientific journals and conferences.
- Lead regulatory submission strategy, responses to regulatory questions, and presentations at regulatory meetings.
Qualifications
- MD or MD/PhD in Rheumatology with 8+ years of clinical development (late-stage clinical studies preferred).
- Clinical experience in Immunology, Rheumatology, or other autoimmune disorders (a plus).
- Demonstrated leadership, organization, and excellent written/verbal communication.
- Ability to work collaboratively in a fast-paced, team-based matrix environment.
- Experience leading global teams (China experience highly valued).
- Comfortable in a demanding start-up culture with evolving processes.
Compensation/Benefits (as stated)
- Base salary range: $286,686 to $307,984 USD; competitive total rewards includes annual performance bonus, equity, full-range benefits, and other incentive compensation.
The Senior Medical Director, Clinical Development Rheumatology will lead the clinical development plan for one or more assets and oversee medical and safety responsibilities for global clinical trials across all phases. Collaborates with Clinical Operations, Clinical Pharmacology, Medical and Scientific Affairs, and externally with KOLs/Investigators, Regulatory Authorities, and Patient Advocacy Groups.
Key Responsibilities
- Lead clinical development plan and overall clinical strategy for multiple global programs.
- Identify unmet medical needs in autoimmune disorders.
- Oversee clinical study design, including authoring study synopses/protocols; collaborating with biostats on the SAP; providing medical monitoring and safety oversight (GCP); interpreting clinical data and authoring CSRs.
- Develop relationships with Investigators, research sites, and KOLs to design trials addressing key medical questions.
- Support publication strategy by preparing/submitting clinical findings to scientific journals and conferences.
- Lead regulatory submission strategy, responses to regulatory questions, and presentations at regulatory meetings.
Qualifications
- MD or MD/PhD in Rheumatology with 8+ years of clinical development (late-stage clinical studies preferred).
- Clinical experience in Immunology, Rheumatology, or other autoimmune disorders (a plus).
- Demonstrated leadership, organization, and excellent written/verbal communication.
- Ability to work collaboratively in a fast-paced, team-based matrix environment.
- Experience leading global teams (China experience highly valued).
- Comfortable in a demanding start-up culture with evolving processes.
Compensation/Benefits (as stated)
- Base salary range: $286,686 to $307,984 USD; competitive total rewards includes annual performance bonus, equity, full-range benefits, and other incentive compensation.