Senior Medical Director, Clinical Development, Oncology (Remote)
Jazz Pharmaceuticals
August 14, 2026
Remote friendly (Home Gardens, CA)
United States
Clinical Research and Development
Position Summary
- The Senior Medical Director, Solid Tumor Oncology, shapes and executes the medical and clinical strategy for solid tumor programs across the drug development lifecycle.
- Provides deep scientific and medical leadership, drives high-quality evidence generation, partners cross-functionally to advance pipeline assets, and represents the organization to external stakeholders (regulatory agencies, investigators, KOLs).
- Accountable for robust clinical development plans, patient-centric trial designs, and scientifically rigorous decision-making aligned with oncology strategy.
Key Responsibilities
Clinical & Medical Leadership
- Provide strategic medical oversight for solid tumor oncology programs from early development through registration and post-approval.
- Serve as medical authority for assigned assets (scientific integrity, patient safety, regulatory compliance).
- Guide trial design, endpoint selection, biomarker strategy, and translational integration.
- Oversee medical monitoring; contribute to safety governance committees (e.g., SMCs, DMCs).
Development Strategy & Execution
- Lead integrated clinical development plans aligned with unmet medical needs and competitive landscape.
- Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to deliver timely, high-quality trials.
- Contribute to portfolio strategy, asset prioritization, and lifecycle management decisions.
Regulatory & External Engagement
- Serve as a key medical contributor in regulatory interactions (e.g., FDA, EMA).
- Support preparation/review of regulatory documents (protocols, CSRs, IBs, IND/CTA submissions, briefing packages).
- Build relationships with investigators, academics, and external experts.
Medical Affairs & Scientific Communication
- Partner with Medical Affairs for development-to-launch and post-marketing activities.
- Contribute to publication strategy, abstracts, congress presentations, and scientific exchange.
- Act as scientific spokesperson internally and externally.
Leadership & Talent Development
- Mentor and lead medical directors and physicians.
- Foster scientific excellence, collaboration, accountability, and patient focus.
- Influence cross-functional teams through thought leadership.
Qualifications
- MD or MD/PhD required; board certification in Oncology, Hematology-Oncology, or related specialty required.
- Advanced clinical training and experience in solid tumor oncology required.
- 10+ years clinical and/or pharmaceutical industry experience in oncology with significant solid tumor focus (thoracic oncology preferred).
- Demonstrated leadership in global clinical development and late-phase programs.
- Proven experience with regulatory interactions and successful filings.
Skills & Competencies (Required)
- Strong strategic thinking and operational execution.
- Excellent communication, influencing, and stakeholder management.
- High ethical standards, sound medical judgment, patient-centric mindset.
Preferred Attributes
- Experience leading registrational or practice-changing thoracic oncology studies.
- Familiarity with biomarker-driven development and precision oncology.
- Comfort in fast-paced, evolving pipeline environments.
Benefits (included)
- Eligible for medical, dental, and vision insurance; 401k; flexible paid vacation.
Application instruction
- If you are a current Jazz employee, apply via the Internal Career site.
- The Senior Medical Director, Solid Tumor Oncology, shapes and executes the medical and clinical strategy for solid tumor programs across the drug development lifecycle.
- Provides deep scientific and medical leadership, drives high-quality evidence generation, partners cross-functionally to advance pipeline assets, and represents the organization to external stakeholders (regulatory agencies, investigators, KOLs).
- Accountable for robust clinical development plans, patient-centric trial designs, and scientifically rigorous decision-making aligned with oncology strategy.
Key Responsibilities
Clinical & Medical Leadership
- Provide strategic medical oversight for solid tumor oncology programs from early development through registration and post-approval.
- Serve as medical authority for assigned assets (scientific integrity, patient safety, regulatory compliance).
- Guide trial design, endpoint selection, biomarker strategy, and translational integration.
- Oversee medical monitoring; contribute to safety governance committees (e.g., SMCs, DMCs).
Development Strategy & Execution
- Lead integrated clinical development plans aligned with unmet medical needs and competitive landscape.
- Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to deliver timely, high-quality trials.
- Contribute to portfolio strategy, asset prioritization, and lifecycle management decisions.
Regulatory & External Engagement
- Serve as a key medical contributor in regulatory interactions (e.g., FDA, EMA).
- Support preparation/review of regulatory documents (protocols, CSRs, IBs, IND/CTA submissions, briefing packages).
- Build relationships with investigators, academics, and external experts.
Medical Affairs & Scientific Communication
- Partner with Medical Affairs for development-to-launch and post-marketing activities.
- Contribute to publication strategy, abstracts, congress presentations, and scientific exchange.
- Act as scientific spokesperson internally and externally.
Leadership & Talent Development
- Mentor and lead medical directors and physicians.
- Foster scientific excellence, collaboration, accountability, and patient focus.
- Influence cross-functional teams through thought leadership.
Qualifications
- MD or MD/PhD required; board certification in Oncology, Hematology-Oncology, or related specialty required.
- Advanced clinical training and experience in solid tumor oncology required.
- 10+ years clinical and/or pharmaceutical industry experience in oncology with significant solid tumor focus (thoracic oncology preferred).
- Demonstrated leadership in global clinical development and late-phase programs.
- Proven experience with regulatory interactions and successful filings.
Skills & Competencies (Required)
- Strong strategic thinking and operational execution.
- Excellent communication, influencing, and stakeholder management.
- High ethical standards, sound medical judgment, patient-centric mindset.
Preferred Attributes
- Experience leading registrational or practice-changing thoracic oncology studies.
- Familiarity with biomarker-driven development and precision oncology.
- Comfort in fast-paced, evolving pipeline environments.
Benefits (included)
- Eligible for medical, dental, and vision insurance; 401k; flexible paid vacation.
Application instruction
- If you are a current Jazz employee, apply via the Internal Career site.