Senior Medical Director, Clinical Development, Oncology (Remote)
Jazz Pharmaceuticals
August 14, 2026
Remote friendly (Philadelphia, PA)
United States
Clinical Research and Development
Position Summary
- The Senior Medical Director, Solid Tumor Oncology, is a senior clinical leader responsible for shaping and executing the medical and clinical strategy for solid tumor programs across the drug development lifecycle.
- Provides deep scientific/medical leadership, drives high-quality evidence generation, partners cross-functionally to advance pipeline assets, and represents the organization to external stakeholders.
- Accountable for robust clinical development plans, patient-centric trial designs, and scientifically rigorous decision-making aligned with the company’s oncology strategy.
Key Responsibilities
Clinical & Medical Leadership
- Provide strategic medical oversight from early development through registration and post-approval.
- Serve as medical authority for assigned assets (scientific integrity, patient safety, regulatory compliance).
- Guide trial design, endpoint selection, biomarker strategy, and translational integration.
- Oversee medical monitoring; contribute to safety governance committees (e.g., SMCs/DMCs).
Development Strategy & Execution
- Lead integrated clinical development plans aligned with unmet need and competitive landscape.
- Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to deliver timely/high-quality trials.
- Contribute to portfolio strategy, asset prioritization, and lifecycle management.
Regulatory & External Engagement
- Act as a key medical contributor in regulatory interactions (e.g., FDA/EMA).
- Support regulatory documents (protocols, CSRs, IBs, IND/CTA submissions, briefing packages).
- Build relationships with investigators, academics, and external experts.
Medical Affairs & Scientific Communication
- Partner with Medical Affairs for development-to-launch and post-marketing transition.
- Support publication and congress activities; serve as scientific spokesperson.
Leadership & Talent Development
- Mentor medical directors/physicians; foster scientific excellence and patient focus.
- Influence cross-functional teams via thought leadership.
Qualifications
- MD or MD/PhD required; board certification in Oncology/Hematology-Oncology or related specialty required.
- Advanced solid tumor oncology training/experience required.
- 10+ years clinical and/or industry experience in oncology with significant solid tumor focus (thoracic oncology preferred).
- Leadership in global clinical development/late-phase programs; regulatory interaction experience.
Preferred Attributes
- Experience leading registrational/practice-changing thoracic oncology studies.
- Familiarity with biomarker-driven development and precision oncology.
- Comfortable in fast-paced, evolving pipeline environments.
Benefits (if you are selected)
- Eligible for medical, dental, vision insurance, 401(k), flexible paid vacation.
Application Instructions
- If you are a current Jazz employee, apply via the Internal Career site.
- The Senior Medical Director, Solid Tumor Oncology, is a senior clinical leader responsible for shaping and executing the medical and clinical strategy for solid tumor programs across the drug development lifecycle.
- Provides deep scientific/medical leadership, drives high-quality evidence generation, partners cross-functionally to advance pipeline assets, and represents the organization to external stakeholders.
- Accountable for robust clinical development plans, patient-centric trial designs, and scientifically rigorous decision-making aligned with the company’s oncology strategy.
Key Responsibilities
Clinical & Medical Leadership
- Provide strategic medical oversight from early development through registration and post-approval.
- Serve as medical authority for assigned assets (scientific integrity, patient safety, regulatory compliance).
- Guide trial design, endpoint selection, biomarker strategy, and translational integration.
- Oversee medical monitoring; contribute to safety governance committees (e.g., SMCs/DMCs).
Development Strategy & Execution
- Lead integrated clinical development plans aligned with unmet need and competitive landscape.
- Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to deliver timely/high-quality trials.
- Contribute to portfolio strategy, asset prioritization, and lifecycle management.
Regulatory & External Engagement
- Act as a key medical contributor in regulatory interactions (e.g., FDA/EMA).
- Support regulatory documents (protocols, CSRs, IBs, IND/CTA submissions, briefing packages).
- Build relationships with investigators, academics, and external experts.
Medical Affairs & Scientific Communication
- Partner with Medical Affairs for development-to-launch and post-marketing transition.
- Support publication and congress activities; serve as scientific spokesperson.
Leadership & Talent Development
- Mentor medical directors/physicians; foster scientific excellence and patient focus.
- Influence cross-functional teams via thought leadership.
Qualifications
- MD or MD/PhD required; board certification in Oncology/Hematology-Oncology or related specialty required.
- Advanced solid tumor oncology training/experience required.
- 10+ years clinical and/or industry experience in oncology with significant solid tumor focus (thoracic oncology preferred).
- Leadership in global clinical development/late-phase programs; regulatory interaction experience.
Preferred Attributes
- Experience leading registrational/practice-changing thoracic oncology studies.
- Familiarity with biomarker-driven development and precision oncology.
- Comfortable in fast-paced, evolving pipeline environments.
Benefits (if you are selected)
- Eligible for medical, dental, vision insurance, 401(k), flexible paid vacation.
Application Instructions
- If you are a current Jazz employee, apply via the Internal Career site.