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Senior Manufacturing Execution Systems (MES) Engineer

AbbVie
June 26, 2026
Remote friendly (Worcester, MA)
United States
$96,500 - $183,500 USD yearly
IT
Job Description
The Manufacturing Execution Systems Engineer will design, implement, and optimize Manufacturing Execution System (MES) solutions across AbbVie’s global manufacturing network, supporting the MES COE Lead’s strategic vision for digital transformation and operational excellence.

Responsibilities
- Collaborate with the Manager, MES and cross-functional teams to deliver high-quality MES solutions aligned with enterprise strategy and standards.
- Lead technical design, configuration, integration, and testing of MES applications for multiple manufacturing modalities and sites.
- Develop, document, and maintain MES best practices, playbooks, and standard operating procedures (SOPs).
- Lead Communities of Practice (COP) meetings; champion template standardization and process simplification using advanced MES capabilities.
- Provide technical leadership and mentorship to MES engineers and collaborators.
- Support adoption of new MES technology and digital transformation initiatives at the site and network levels.
- Analyze manufacturing processes and data to identify MES-driven process improvement, automation, and harmonization opportunities.
- Ensure compliance with cGMP, regulatory requirements, and AbbVie ways of working in all MES engineering activities.
- Contribute to governance, technical documentation, and training for MES solutions; support New Instance MES delivery through Global Recipe Templates.

Qualifications
- Bachelor’s degree in Software Engineering, Science, IT, or related field.
- 6+ years experience with MES in pharmaceutical manufacturing, automation, or regulated environments.
- Solid understanding of digital manufacturing, MES operations, and enterprise IT/OT integration.
- Experience with process improvement, system analysis, and technical documentation in multi-site/global environments.
- Demonstrated ability to collaborate across multidisciplinary teams and communicate effectively.
- Working knowledge of cGMP and pharma regulatory/quality compliance.
- Experience with MES platforms, preferably POMS Aquila.
- Ability to train/mentor junior staff and contribute to knowledge sharing.
- Strong problem-solving, analytical, and organizational skills.