Senior Manager – Partner, Global Health Economics

Role Summary

Senior Manager – Partner, Global Health Economics leads health economics strategies for Takeda oncology medicines and drives hands-on economic assessments across development stages using HE models, systematic literature reviews, indirect treatment comparisons, and analyses of trial and real-world data. Collaborates with cross-functional partners to inform clinical development plans, evidence generation activities, global market access plans, and pricing decisions. Leads development of Global HE materials and supports country adaptations to regional and local operating company PVA and HE leads, overseeing country roll-out and training on global HE materials and responding to payer inquiries. Proposes and co-leads publication plans for portfolio medicines through lifecycle management aligned with Global Oncology HE and Global Oncology Pricing, Value & Access priorities. Location: Boston, MA.

Responsibilities

• Develop early HE models and comparative efficacy/effectiveness analyses to contribute to target product profiles and clinical development plans, understanding HE outcomes needed for market access and planning HTA across markets (including JCA).
• Lead development of state-of-the-art HE models and studies (e.g., SLRs, ITCs) with evidentiary support to withstand HTA scrutiny.
• Lead training to Regions and LOCs on product value, new evidence and HE studies and models.
• Contribute to evidence generation planning to demonstrate product value to payers, HTA bodies, and market access decision makers; ensure payer and HE evidence needs are incorporated into Global, Regional and Local activities.
• Evaluate anticipated HTA outcomes (including JCA) and implications for value positioning; shape ongoing evidence generation plans in partnership with Global PVA, GEO and GMAO.
• Make recommendations to cross-functional partners about additional data generation (clinical trials, real-world evidence such as registries) based on payer/HTA requirements.
• Ensure integration of payer-relevant HE endpoints and evidence needs in clinical development plans.
• Establish understanding of burden of disease, unmet need and appropriate comparator to inform Global Value Proposition and market access.
• Support Global PVA colleagues in developing global value propositions and ensure compelling payer value messages; update the product value platform (Value Story, Global Value Dossiers, Objection Handler, Global Pricing Guidance).
• Maintain awareness of evolving global HTA and reimbursement landscape and the evidentiary needs of decision-makers to guide HE and market access strategies.
• Communicate HE messages effectively in manuscripts, posters, and publications; support development of communication tools for clinicians and payers as needed.
• Foster collaboration and manage partnerships and consultants (e.g., Regions/LOCs, US Payer Marketing and Market Access, GEO, GMAO, Biostatistics, GEM, Project Leadership, Finance, Corporate Communications, Business Development).
• Ensure excellence in HE activities and stay up to date on innovative HE, HTA, and RWE methods.

Qualifications

• Required: Doctorate with 1+ years of experience, or Master's with 2+ years of experience, or Bachelor's with 4+ years of experience in the healthcare industry with direct experience in global product value proposition development (industry or consulting) and interaction with payers, HTA bodies, relevant policymakers, and strong patient-centered focus.
• Required: Good understanding of the global payer environment and ex-US payer landscape including HTA trends and guidance (e.g., NICE, CADTH, PBAC), along with knowledge of US Medicare (Part D), ICER in the US and trends in Emerging Markets (e.g., China) – including reimbursement methodologies, pricing/reimbursement authorities’ decision-making process and current reimbursement issues.
• Required: Knowledge and hands-on experience in health economics, HTA tools, methods and filings, SLRs, ITCs, statistical analyses and economic modelling.
• Required: Understanding of clinical and epidemiological information, innovative global pricing models, all phases of drug development methods of analysis of large databases (e.g., claims data, electronic health records) and the major areas of Outcomes Research (PROs, patients preferences).
• Required: Ability to work in a highly matrixed organization.
• Required: Strong analytical capabilities and excellent communication skills (written and oral).
• Required: Demonstrated problem solving capability.
• Required: Influencing skills with the ability to effectively drive decision making.
• Required: Ability to translate technical issues to non-technical experts.
• Required: 5 to 10% domestic and/or international travel.
• Preferred: Previous experience in Oncology.
• Preferred: A combination of Global and US HE-related experience with knowledge of HTA requirements AND experience in HTA submissions.
• Preferred: Peer-reviewed publications and/or oral and poster presentations at scientific conferences.

Skills

• Health economics modeling and analyses (SLRs, ITCs); economic modelling.
• Proficiency with trial and real-world data analyses and RWE approaches.
• Knowledge of HTA processes and payer communications; ability to translate HE results for clinicians and payers.
• Strong analytical and quantitative skills; ability to work in a matrixed environment; strong communication and collaboration.
• Project management and cross-functional influencing abilities.

Education

• Doctorate with 1+ years of experience, Master's with 2+ years of experience or Bachelor's with 4+ years of experience in the healthcare industry with direct experience in global product value proposition development and interaction with payers, HTA bodies, policymakers and strong patient-centered focus.

Additional Requirements

• 5 to 10% domestic and/or international travel required.