Senior Manager, Manufacturing Operations
Halozyme, Inc.
August 21, 2026
Remote friendly (Minnetonka, MN)
United States
Operations
Position Summary
The Senior Manager, Manufacturing Operations leads the Manufacturing Operations function at the Minnetonka facility and is accountable for safe, compliant, and efficient cGMP assembly, labeling, packaging, and related production activities for combination pharmaceutical products.
Essential Functions And Responsibilities
- Lead safe, compliant, and efficient multi-shift cGMP manufacturing operations (assembly, labeling, packaging) supporting clinical/commercial product supply.
- Translate site/business objectives into manufacturing strategy, staffing plans, capacity models, operating priorities, and execution roadmaps.
- Drive manufacturing performance via resource planning, escalation practices, risk-based decision-making, and metrics (safety, quality, schedule adherence, throughput, utilization, productivity, yield, right-first-time).
- Lead monthly cross-functional meetings to review and improve performance.
- Lead continuous improvement/operational excellence to improve stability, reliability, scalability; execute strategic initiatives.
- Ensure Manufacturing Operations complies with cGMP and the quality management system.
- Build/coach/mentor/develop manufacturing leaders and team members; strengthen technical capability, training, qualification, procedural compliance, ownership, and succession readiness.
- Provide executive-ready communication, operational updates, business case input, and escalation support.
- Foster cross-functional governance with Quality, Engineering, Facilities, Materials Management, Planning, IT, EHS, HR, Supply Chain, and external partners.
- Operate/monitor manufacturing equipment as needed.
Education/Experience/Requirements
- Bachelor’s degree in Engineering, Science, Operations, Supply Chain, Business, or related technical discipline required; Science/Engineering preferred.
- 8+ years in medical device or pharmaceutical production with robotics/automation.
- 5+ years managing manufacturing line teams for production/packaging of Medical Device and/or pharmaceutical products.
- Experience translating business/site objectives into manufacturing strategies, capacity, staffing models, execution roadmaps, and outcomes.
Skills (Preferred)
- Clinical-to-commercial scale-up, production expansion, new product introduction, technology transfer.
- Automation implementation; MES, electronic batch records, ERP/production planning, digital workflows, data-driven performance.
- Strong cGMP/quality systems knowledge; ISO/regulatory/audit readiness; deviations, CAPA, change control, validation, inspection support.
- Lean/Six Sigma/5S/standard work/visual management/root-cause analysis.
- Transformational change leadership; risk-based decisions; managing constraints in fast-paced environments.
Compensation
- Most likely base pay range: $140K–$185K per year. Total compensation may include bonuses, sales incentives, and equity awards.
The Senior Manager, Manufacturing Operations leads the Manufacturing Operations function at the Minnetonka facility and is accountable for safe, compliant, and efficient cGMP assembly, labeling, packaging, and related production activities for combination pharmaceutical products.
Essential Functions And Responsibilities
- Lead safe, compliant, and efficient multi-shift cGMP manufacturing operations (assembly, labeling, packaging) supporting clinical/commercial product supply.
- Translate site/business objectives into manufacturing strategy, staffing plans, capacity models, operating priorities, and execution roadmaps.
- Drive manufacturing performance via resource planning, escalation practices, risk-based decision-making, and metrics (safety, quality, schedule adherence, throughput, utilization, productivity, yield, right-first-time).
- Lead monthly cross-functional meetings to review and improve performance.
- Lead continuous improvement/operational excellence to improve stability, reliability, scalability; execute strategic initiatives.
- Ensure Manufacturing Operations complies with cGMP and the quality management system.
- Build/coach/mentor/develop manufacturing leaders and team members; strengthen technical capability, training, qualification, procedural compliance, ownership, and succession readiness.
- Provide executive-ready communication, operational updates, business case input, and escalation support.
- Foster cross-functional governance with Quality, Engineering, Facilities, Materials Management, Planning, IT, EHS, HR, Supply Chain, and external partners.
- Operate/monitor manufacturing equipment as needed.
Education/Experience/Requirements
- Bachelor’s degree in Engineering, Science, Operations, Supply Chain, Business, or related technical discipline required; Science/Engineering preferred.
- 8+ years in medical device or pharmaceutical production with robotics/automation.
- 5+ years managing manufacturing line teams for production/packaging of Medical Device and/or pharmaceutical products.
- Experience translating business/site objectives into manufacturing strategies, capacity, staffing models, execution roadmaps, and outcomes.
Skills (Preferred)
- Clinical-to-commercial scale-up, production expansion, new product introduction, technology transfer.
- Automation implementation; MES, electronic batch records, ERP/production planning, digital workflows, data-driven performance.
- Strong cGMP/quality systems knowledge; ISO/regulatory/audit readiness; deviations, CAPA, change control, validation, inspection support.
- Lean/Six Sigma/5S/standard work/visual management/root-cause analysis.
- Transformational change leadership; risk-based decisions; managing constraints in fast-paced environments.
Compensation
- Most likely base pay range: $140K–$185K per year. Total compensation may include bonuses, sales incentives, and equity awards.