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Senior Manager, IT Technical Security

Cytokinetics Incorporated
October 22, 2026
Full-time
Remote friendly (South San Francisco, California)
United States
IT
Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
Cytokinetics continues to mature its Cybersecurity Program including its policies, procedures, controls, guidelines, and technologies. This role is responsible for performing the day-to-day oversight, implementation, and operations of technical platforms that support the broader Cybersecurity Program.
This individual should have a firm understanding of key technologies and features (e.g., authentication and access management platforms, multi-factor authentication technologies, end-point detection and remediation tools, OS and application hardening, cloud computing infrastructures, vulnerability and patch management, etc.).
This role is located in Cytokinetics’ South San Francisco headquarters.
Responsibilities:
Monitor the security posture of enterprise technology environments across cloud and on-premises infrastructure, endpoints, networks, identity platforms, and business applications.
Maintain a structured process for aggregating, analyzing, and tracking vulnerability data to identify trends, prioritize risks, monitor remediation progress, and support informed decision-making.
Collaborate with internal stakeholders and external partners to assess, prioritize, and remediate security issues using a risk-based approach that balances business needs, operational impact, and security requirements.
Review critical infrastructure platform configurations (e.g., Exchange, SharePoint, Teams, Box, Azure, and AWS, Firewalls) and work with internal and external support teams to harden in accordance with current security requirements and standards.
Maintain a technical security scorecard and report to CISO and IT on a periodic basis.
Own and coordinate the investigation and response to cybersecurity events and incidents, including triage, containment, remediation, recovery, and follow-up.
Qualifications:
8+ years of relevant IT or cybersecurity experience, including 5+ years implementing and managing enterprise security platforms; a bachelor’s degree in a related field or equivalent practical experience is preferred.
Must have firm understanding of NIST framework and supporting procedures and controls.
Strong verbal and written communication including presentation of complex information to the broad company in an easy and consumable format.
Must have strong collaboration skills.
Must be highly organized and curious.
Be a highly collaborative team member with other IT as well as business colleagues to drive down security risk balanced with appropriate risk acceptance and soft-touch education as necessary.
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Pay Range:
The expected salary range for this position based on the primary location of South San Francisco, CA is $201,600-$235,200. The base pay offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.
Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.
Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.
Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.
Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.
Here are some ways to check for authenticity:
We do not conduct job interviews through non-standard text messaging applications
We will never request personal information such as banking details until after an official offer has been accepted and verified
We will never request that you purchase equipment or other items when interviewing or hiring
If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at talentacquisition@cytokinetics.com
Please visit our website at: www.cytokinetics.com
Cytokinetics is an Equal Opportunity Employer