Overview

The Senior Manager, Global Planning is a key member of the Supply Chain organization responsible for the planning and oversight of Drug Substance and Drug Product manufacturing for the early stage pipeline. This position works closely with key stakeholders including: Program Teams, Process Sciences, CMC, Internal and External Manufacturing, Quality Assurance (QA), Global Logistics and Regulatory Affairs, to ensure seamless supply of Clinical Trial Material. This role will also be a key contributor to the Global CS&OP process with development of the Early Stage and Partner S&OP Process. A successful candidate will be skilled at understanding the Clinical Supply and Operations planning process and the challenges/timelines of early stage development. In addition, a successful candidate will demonstrate the ability to work independently with only minimal guidance on highly complex situations.

This role follows a hybrid work model, with an expectation of being on-site in our Cambridge, MA office a minimum of two days per week. Additional in-person presence may be required based on business needs, team meetings, or project demands.

Key Responsibilities

• Key contributor to clinical supply and operations planning monthly team meeting (CS&OP)
• Contribute and advise on Partner Sales and Operation Demand Reviews.
• Work cross-functionally to develop scenario plans and strategies that result in production plans that meet program, capacity, and budget requirements.
• Leads and supports other in the group to provide strategic planning and execution recommendations.
• Collaborate with external partners to ensure Drug Substance and Drug Product supply needs are met in line with contractual obligations.
• Develop short and long term manufacturing plans using clinical development plans from program management and CMC.
• Partner with CMC, Process Sciences, Program Team, QA, QC, Finance and Materials Management to ensure material availability is in line with clinical program timelines and budget.
• Troubleshoot and identify root causes, and suggest solutions to meet project objectives.
• Develops Annual Long Range Manufacturing Plans based on available information, highlighting areas of constraint.
• Utilize and oversee SAP master data integrity to ensure inventory and order management is accurate and precise.
• Build strong relationships and communication with all functions to ensure information is accurate for planning purposes.

Qualifications

• B.S. in Business, Supply Chain, Engineering or science-related discipline. Advanced degree preferred.
• A minimum of 5 years of relevant experience, 7 years preferred, in a Manufacturing or Supply Chain role with experience in Production, Planning, or Scheduling.
• Excellent math and computer skills required, including Microsoft Office/Excel/PowerPoint.
• Good knowledge of computerized production and inventory control systems (SAP) and documentation practices.
• Demonstrated ability to manage multiple priorities against ambitious timelines. Strong project management ability.
• Exceptional communication skills and ability to communicate to multiple levels within company. Ability to present complex information to all levels of the organization.
• Strong problem-solving skills and ability to work cross-functionally as critical member of site team.
• Experience with site capacity planning and/or global product supply planning and knowledge of Biotech, Pharmaceutical Sales & Operations Planning processes.
• ERP planning experience a plus

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

Equal Employment Opportunity

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.