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Senior Manager, Global Medical Affairs Strategy, RNA Therapeutics

Sarepta Therapeutics
September 26, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Medical Affairs
Role: Senior Manager, Global Medical Affairs Strategy focusing on RNA therapeutics, supporting Sarepta's programs in Duchenne muscular dystrophy and other neuromuscular diseases with genetic medicine approaches. Responsibilities include developing and executing medical strategies for product launch and lifecycle management, identifying data gaps, generating scientific narratives, analyzing clinical and real-world data, and supporting scientific communications for congresses and advisory boards. The role involves collaboration with cross-functional teams, managing medical content, vendor oversight, and training internal stakeholders. Qualifications: Doctorate degree (MD, PhD, PharmD); 3+ years industry experience, preferably in rare diseases, neuromuscular disorders, or related fields. Skills include strong scientific communication, project management, and ability to operate in matrix organizations. Preferred: Experience in neuromuscular, neurology, or rare disease therapeutic areas, and familiarity with GxP and medical review processes. High-Value: Focus on gene therapies and siRNA modalities, supporting product development and lifecycle management in a highly regulated environment, with responsibilities spanning scientific strategy, data analysis, and external engagement. Work setup: Hybrid in the U.S., with domestic and international travel as needed.