Senior Manager, FP&A – R&D Pipeline

Senior Manager, FP&A – R&D Pipeline

Who We Are

Cogent Biosciences is a publicly traded biotechnology company focused on developing precision therapies for genetically defined diseases. The most advanced clinical program, bezuclastinib, is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis (SM), a serious disease caused by unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Top-line results from registration-directed trials in NonAdvanced SM, Advanced SM and GIST are expected in 2025. The company also has an ongoing Phase 1 study of its novel internally discovered FGFR2 inhibitor. In addition, the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting serious, genetically driven diseases targeting mutations in ErbB2, PI3Kα and KRAS.

Our Team

Cogent Culture

We are seeking a strong individual contributor to join our Finance team as Senior Manager, FP&A supporting R&D and pipeline programs. This role will lead forecasting and financial planning across clinical development and early-stage research. The ideal candidate combines domain knowledge in biotech R&D with hands-on experience working across ERPs, planning tools, and large datasets to drive accuracy, transparency, and insight in the forecasting process.

Responsibilities

• Serve as the primary finance partner for Clinical Development, Regulatory, Program Management, and R&D leadership
• Build and maintain program-level forecasts for clinical trials, and research initiatives
• Support scenario modeling, portfolio views, and long-range planning for pipeline investment decisions
• Own the forecast-to-actual process for R&D spend, including accrual support
• Collaborate closely with Accounting during monthly and quarterly closes to ensure accuracy of R&D-related entries, accruals, and capitalization
• Work with Head of FP&A to develop reports and tools that streamline budgeting, forecasting, and management review
• Leverage systems (NetSuite, Adaptive Insights or similar) and Excell to consolidate and visualize financial data
• Actively contribute to the budgeting, forecast updates, and corporate planning cycles
• Consolidate inputs across all functions into a draft R&D financial rollup for review with the CFO and Head of FP&A

Qualifications

• 6+ years of progressive experience in FP&A, with at least 3 years supporting R&D or clinical operations in the biotech/pharma industry
• Deep understanding of clinical trial forecasting and key cost drivers
• Strong financial modeling and analytical skills, with experience owning complex budgets and scenarios
• Experience with ERP and planning systems (NetSuite, Adaptive Insights, etc.) and a high level of comfort working with data
• Advanced Excel and proficiency in data tools
• Ability to work independently and collaboratively across cross-functional teams
• Excellent communication and organizational skills
• Bachelor’s degree in Finance, Accounting, Economics, or related field; MBA or CPA a plus

Our Locations

Waltham, MA: Our Boston office includes an open office layout that has recently undergone a makeover designed for collaboration and giving our employees the best work place possible. Free access is provided for both on-site parking and gym facilities in the building.

Boulder, CO: We have just moved into our new state-of-the art Research Facility in the fast-growing biopharmaceutical hub in the greater Denver/Boulder corridor. Our CEO is based full-time in this location and we are proud to call this the home of Cogent’s discovery research organization.

Our Offer To You

To attract the very best talent, we offer a generous benefits package that includes competitive pay, performance-based bonus, stock options, insurance coverage (health, dental, life, and disability), competitive time-off, a 401(k) plan, and commuter/parking benefits.

We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need.

Target Bonus: 15%

• Exact compensation will vary based on skills, experience, education and location