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Senior Manager, Forecasting & Analytics

Sarepta Therapeutics
June 27, 2026
Remote friendly (Cambridge, MA)
United States
Corporate Functions
The Senior Manager, Forecasting and Analytics is responsible for building robust commercial forecasts, generating decision-ready analyses, and developing perspectives that support the commercial success of Sarepta’s in-line and pipeline portfolio. Partners with Competitive Intelligence, Market Research, Sales, Finance, Business Performance, Market Access, Patient Services, and International Business to develop pressure-tested forecasts, commercial perspectives, and business targets.

Primary Responsibilities Include:
- Build, own, and maintain lifecycle-appropriate forecasting models for U.S. and global in-line and pipeline portfolio.
- Develop forecast scenarios, sensitivity analyses, business opportunity estimates, and near- and long-term therapy adoption projections.
- Translate strategic, operational, and financial drivers into forecast assumptions and models.
- Evolve forecasting capabilities through model refreshes, scenario analyses, and variance reporting.
- Support planning processes (S&OP, LRP, LEs) to reflect risks and uncertainties in commercial decisions.
- Support quarterly HCP targeting activity for four in-market products.
- Lead development and management of forecast models for pipeline therapies (including SiRNA programs).
- Drive ad hoc analyses to refine assumptions for board and leadership discussions.
- Produce periodic demand forecasts with Commercial, Finance, and Tech Ops.
- Monitor market dynamics and update forecasts based on relevant industry and therapeutic-area developments.
- Build cross-functional relationships; perform other related duties as needed.

Desired Education and Skills:
- Bachelor’s degree with 7–9 years in a scientific/quantitative/stats field required; master’s preferred.
- 5+ years forecasting and analytics experience in biopharma (rare disease preferred); consulting experience a plus.
- Excellent communication for Commercial Leadership/Executive Committee/Board discussions.
- Experience using AI tools/agents to automate recurring analyses.
- Advanced Excel and Tableau (or similar); preferred SQL/Python (or similar).
- Exceptional attention to detail; strong logical/critical thinking; ability for quick back-of-the-envelope analyses.
- Strong project management with ability to manage multiple priorities.

Benefits (if applicable/explicit): Physical and Emotional Wellness; Financial Wellness; Support for Caregivers.

Application instructions: Apply if you are solution-oriented, comfortable with ambiguity and candor, and value kindness and integrity.

Other: Hybrid role; work on site at U.S. facilities and/or attend in-person events. Target salary range: $136,000–$170,000/year. Candidates must be authorized to work in the U.S.