Senior Manager, Clinical Operations
Travere Therapeutics
August 14, 2026
On-site
San Diego Metropolitan Area
Clinical Research and Development
Position Summary:
The Senior Manager, Clinical Operations is responsible for supervision and execution of clinical operations for Phase 1–3 clinical trials, coordinating and managing daily trial activities with internal teams and Contract Research Organizations (CROs).
Responsibilities:
- Provide daily oversight of internal study teams, full-service CROs, clinical sites, and third-party vendors to ensure successful trial implementation.
- Triage, resolve, or escalate study issues to Clinical Operations Management.
- Manage unpredictable scenarios to meet project timelines using understanding of study protocols.
- Manage assigned study/program area including timelines, budgets, and Study Management Team (SMT); deliver milestones on time.
- Guide cross-functional execution (e.g., Biometrics, PV) in compliance with study plans, SOPs, and ICH/GCP.
- Track study status, timelines, enrollment, regulatory documentation, and site start-up.
- Develop/provide input into clinical documents (protocol, ICF templates, study plans/tools, site materials).
- Oversee CRO/vendor budgets and track/forecast changes with Strategic Procurement.
- Track/manage trial materials, supplies, and laboratory samples.
- Lead cross-functional activities to establish and meet SMT goals; communicate issues and mitigations.
- Provide basic strategic input into study management.
Qualifications & Requirements:
- Bachelor’s degree (or equivalent education/experience).
- 7+ years clinical trial experience; 2+ years managing clinical studies at a sponsor or CRO.
- Experience with global regulatory/compliance requirements (US CFR, EU CTD, ICH E6(R2) GCP).
- Phase 1–3 (and/or international studies) preferred.
Skills:
- Courage, community spirit, patient focus, teamwork.
- Proactive, self-starter; strong problem-solving and communication.
- Ability to set goals, identify root causes, and implement solutions.
- Proficient MS Office and timeline software (e.g., MS Project, Smartsheet); experience with IRT/eTMF preferred.
- Ability to travel 10–20% and work onsite in San Diego (not 100% remote).
Benefits:
- Premium health, financial, work-life/well-being; wellness/employee support; life insurance, disability; retirement match; generous paid time off.
Application Instructions:
- Travere will accept applications on an ongoing basis until a candidate is selected.
The Senior Manager, Clinical Operations is responsible for supervision and execution of clinical operations for Phase 1–3 clinical trials, coordinating and managing daily trial activities with internal teams and Contract Research Organizations (CROs).
Responsibilities:
- Provide daily oversight of internal study teams, full-service CROs, clinical sites, and third-party vendors to ensure successful trial implementation.
- Triage, resolve, or escalate study issues to Clinical Operations Management.
- Manage unpredictable scenarios to meet project timelines using understanding of study protocols.
- Manage assigned study/program area including timelines, budgets, and Study Management Team (SMT); deliver milestones on time.
- Guide cross-functional execution (e.g., Biometrics, PV) in compliance with study plans, SOPs, and ICH/GCP.
- Track study status, timelines, enrollment, regulatory documentation, and site start-up.
- Develop/provide input into clinical documents (protocol, ICF templates, study plans/tools, site materials).
- Oversee CRO/vendor budgets and track/forecast changes with Strategic Procurement.
- Track/manage trial materials, supplies, and laboratory samples.
- Lead cross-functional activities to establish and meet SMT goals; communicate issues and mitigations.
- Provide basic strategic input into study management.
Qualifications & Requirements:
- Bachelor’s degree (or equivalent education/experience).
- 7+ years clinical trial experience; 2+ years managing clinical studies at a sponsor or CRO.
- Experience with global regulatory/compliance requirements (US CFR, EU CTD, ICH E6(R2) GCP).
- Phase 1–3 (and/or international studies) preferred.
Skills:
- Courage, community spirit, patient focus, teamwork.
- Proactive, self-starter; strong problem-solving and communication.
- Ability to set goals, identify root causes, and implement solutions.
- Proficient MS Office and timeline software (e.g., MS Project, Smartsheet); experience with IRT/eTMF preferred.
- Ability to travel 10–20% and work onsite in San Diego (not 100% remote).
Benefits:
- Premium health, financial, work-life/well-being; wellness/employee support; life insurance, disability; retirement match; generous paid time off.
Application Instructions:
- Travere will accept applications on an ongoing basis until a candidate is selected.