Senior Manager, Clinical Informatics
Tango Therapeutics
September 04, 2026
Remote friendly (Boston, MA)
United States
IT
Summary:
The Senior Manager, Clinical Informatics leads the design, implementation, and continuous improvement of clinical data flow, integration, analytics, visualization, and reporting across the clinical development portfolio in a validated GxP environment.
Responsibilities:
- Partner with Clinical Trial Teams and stakeholders to define and implement clinical data flow, integration, visualization, and analytics strategies.
- Lead development and maintenance of IRT and eCOA systems and processes; oversee IRT/eCOA vendors for protocol and study objective alignment.
- Translate business requirements into scalable reporting, dashboards, analytics, trial supply management, and data visualization solutions.
- Drive standardization of data flows, integrations, business rules, reporting processes, and analytics frameworks to improve governance and efficiency.
- Lead implementation, integration, enhancement, and lifecycle management of clinical systems, analytics platforms, and visualization solutions.
- Oversee vendors/partners, system configurations, and data integrations to meet requirements, quality standards, timelines, and regulatory expectations.
- Drive adoption of automation, advanced analytics, AI/ML, and cloud technologies within validated GxP.
- Ensure compliance with regulatory requirements, computerized system validation, data governance, and inspection readiness.
- Support audits, inspections, and health authority interactions.
- Develop user training and guidance; contribute to continuous improvement initiatives.
Qualifications/Skills:
- 7+ years in Clinical Informatics/Data Management/Statistical Programming/Clinical Systems (biotech/pharma/CRO).
- Experience implementing clinical data flow, reporting, visualization, and analytics in regulated environments.
- Experience with IRT/eCOA systems (configurations, implementations, enhancements, integrations) and leading UAT.
- Experience with CSV/CSA in regulated GxP systems; external data integrations (CROs/labs/imaging).
- Experience with audits/inspections/inspection readiness.
- Cloud, automation, and digital transformation experience.
- Knowledge of clinical trial processes, data governance; data standards (CDISC, CDASH, SDTM, ADaM, OMOP, BRIDG).
- Knowledge of ICH-GCP, FDA, EU CTR, computerized system validation requirements.
- Expertise in data visualization/analytics/dashboards and tools (Spotfire, Tableau/ Elluminate, Power BI or equivalent).
- Strong project and vendor management; analytical and stakeholder management skills.
Compensation:
- Salary range: $144,800—$217,200 USD.
The Senior Manager, Clinical Informatics leads the design, implementation, and continuous improvement of clinical data flow, integration, analytics, visualization, and reporting across the clinical development portfolio in a validated GxP environment.
Responsibilities:
- Partner with Clinical Trial Teams and stakeholders to define and implement clinical data flow, integration, visualization, and analytics strategies.
- Lead development and maintenance of IRT and eCOA systems and processes; oversee IRT/eCOA vendors for protocol and study objective alignment.
- Translate business requirements into scalable reporting, dashboards, analytics, trial supply management, and data visualization solutions.
- Drive standardization of data flows, integrations, business rules, reporting processes, and analytics frameworks to improve governance and efficiency.
- Lead implementation, integration, enhancement, and lifecycle management of clinical systems, analytics platforms, and visualization solutions.
- Oversee vendors/partners, system configurations, and data integrations to meet requirements, quality standards, timelines, and regulatory expectations.
- Drive adoption of automation, advanced analytics, AI/ML, and cloud technologies within validated GxP.
- Ensure compliance with regulatory requirements, computerized system validation, data governance, and inspection readiness.
- Support audits, inspections, and health authority interactions.
- Develop user training and guidance; contribute to continuous improvement initiatives.
Qualifications/Skills:
- 7+ years in Clinical Informatics/Data Management/Statistical Programming/Clinical Systems (biotech/pharma/CRO).
- Experience implementing clinical data flow, reporting, visualization, and analytics in regulated environments.
- Experience with IRT/eCOA systems (configurations, implementations, enhancements, integrations) and leading UAT.
- Experience with CSV/CSA in regulated GxP systems; external data integrations (CROs/labs/imaging).
- Experience with audits/inspections/inspection readiness.
- Cloud, automation, and digital transformation experience.
- Knowledge of clinical trial processes, data governance; data standards (CDISC, CDASH, SDTM, ADaM, OMOP, BRIDG).
- Knowledge of ICH-GCP, FDA, EU CTR, computerized system validation requirements.
- Expertise in data visualization/analytics/dashboards and tools (Spotfire, Tableau/ Elluminate, Power BI or equivalent).
- Strong project and vendor management; analytical and stakeholder management skills.
Compensation:
- Salary range: $144,800—$217,200 USD.