Senior IT Support Engineer
uniQure
September 02, 2026
Remote friendly (Lexington, MA)
United States
IT
Key responsibilities
- Administer and support Microsoft 365 for the Lexington office (Exchange Online, SharePoint Online, OneDrive): configuration, licensing, and end-user support.
- Administer Entra ID identity and access management (user/group lifecycle, role/access assignment, conditional access, MFA policies, periodic access reviews).
- Own Microsoft Teams support for Lexington (Teams calling, meeting rooms, collaboration governance, troubleshooting).
- Co-own global onboarding standards (account/access/device provisioning) with Amsterdam; maintain standards in Intune (device enrollment, configuration profiles, compliance policies, application deployment).
- Serve as senior escalation point to Lexington Support Engineers; provide technical guidance/standards for issue resolution.
- Respond to and resolve IT requests/queries via the IT ticket system; make improvement recommendations to engineering/architecture teams.
- Provide helpdesk support across a mixed macOS/Windows environment, plus mobile telephony and meeting-room/video equipment.
- Perform application/user management for assigned applications (first/second contact) and act as backup Application Manager for specified systems.
- Support compliance and audits; handle identity/endpoint/application security tasks and software updates per change control.
- Manage IT asset and knowledge inventory.
Qualifications & required/preferred skills
- Hands-on experience administering/supporting Microsoft 365, Entra ID, and Microsoft Teams (incl. Teams calling) in an international enterprise environment.
- College/ICT or equivalent in Computer Sciences.
- Minimum 8 years in a technology services role (Support Engineer/Service Administrator), using ITIL practices (incident/request/change/knowledge); ITIL certification a plus.
- Strong Intune experience (enrollment, config profiles, compliance policies, application deployment).
- Strong macOS support; solid Windows client support; Intune management across both platforms preferred.
- Ability to support remote/field users (remote troubleshooting, management, provisioning).
- Strong communication skills; commercial org experience; multicultural international experience preferred.
- Physically able to manage/support workplaces.
- Administer and support Microsoft 365 for the Lexington office (Exchange Online, SharePoint Online, OneDrive): configuration, licensing, and end-user support.
- Administer Entra ID identity and access management (user/group lifecycle, role/access assignment, conditional access, MFA policies, periodic access reviews).
- Own Microsoft Teams support for Lexington (Teams calling, meeting rooms, collaboration governance, troubleshooting).
- Co-own global onboarding standards (account/access/device provisioning) with Amsterdam; maintain standards in Intune (device enrollment, configuration profiles, compliance policies, application deployment).
- Serve as senior escalation point to Lexington Support Engineers; provide technical guidance/standards for issue resolution.
- Respond to and resolve IT requests/queries via the IT ticket system; make improvement recommendations to engineering/architecture teams.
- Provide helpdesk support across a mixed macOS/Windows environment, plus mobile telephony and meeting-room/video equipment.
- Perform application/user management for assigned applications (first/second contact) and act as backup Application Manager for specified systems.
- Support compliance and audits; handle identity/endpoint/application security tasks and software updates per change control.
- Manage IT asset and knowledge inventory.
Qualifications & required/preferred skills
- Hands-on experience administering/supporting Microsoft 365, Entra ID, and Microsoft Teams (incl. Teams calling) in an international enterprise environment.
- College/ICT or equivalent in Computer Sciences.
- Minimum 8 years in a technology services role (Support Engineer/Service Administrator), using ITIL practices (incident/request/change/knowledge); ITIL certification a plus.
- Strong Intune experience (enrollment, config profiles, compliance policies, application deployment).
- Strong macOS support; solid Windows client support; Intune management across both platforms preferred.
- Ability to support remote/field users (remote troubleshooting, management, provisioning).
- Strong communication skills; commercial org experience; multicultural international experience preferred.
- Physically able to manage/support workplaces.