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Senior Infrastructure Architect

Kymera Therapeutics
Remote friendly (Greater Boston)
United States
$160,000 - $240,000 USD yearly
IT

Role Summary

Senior Infrastructure Architect responsible for driving the next evolution of cloud, networking, and identity platforms. This is a senior IC role with broad architectural ownership, hands-on engineering responsibility, and influence across the entire tech stack. You will work in a high-autonomy environment partnering with engineering teams to own systems end-to-end.

Responsibilities

  • You will serve as the technical lead for infrastructure across AWS, identity, networking, and endpoint platforms—owning design, implementation, and continuous improvement.
  • Cloud, Compute & Data Infrastructure: Architect and build scalable, high-availability AWS environments; design secure, performant data pipelines from on-prem systems to AWS; support Linux-based compute workflows, HPC-style workloads, distributed pipelines, and containerized environments; automate using Infrastructure-as-Code (Terraform, CloudFormation) and modern orchestration.
  • Networking & Hybrid Connectivity: Own enterprise networking including routing, switching, firewalls, SD-WAN, VPNs, and hybrid cloud connectivity; build resilient multi-path connectivity and dual-internet redundancy.
  • Identity, Endpoint & Security Foundations: Evolve Azure/Entra hybrid identity with Conditional Access, authentication policies, lifecycle management, and directory sync; improve endpoint security and compliance via Intune policies and zero-trust; partner with InfoSec on cloud governance and service-to-service authentication standards.
  • Collaboration & Engineering Partnership: Work with R&D engineers, data scientists, and application teams; build observability into everything (CloudWatch, Grafana, telemetry pipelines, predictive alerting); create useful technical documentation, diagrams, and runbooks.

Qualifications

  • Required: 5+ years of hands-on experience in infrastructure, cloud architecture, systems engineering, or platform engineering; strong AWS experience (AWS Solutions Architect Associate required; Professional highly preferred); deep knowledge of AWS compute, networking, security/IAM, cost optimization, and operational tooling; solid networking fundamentals (routing, switching, firewalls, VPNs, hybrid cloud networking, SD-WAN); comfort supporting Linux compute environments, distributed workloads, and automated pipelines; proficiency in scripting/automation (Python, Bash, or similar); hands-on experience with Terraform or CloudFormation.
  • Preferred: AWS Solutions Architect Professional certification; working knowledge of Azure AD / Entra ID hybrid identity, Conditional Access, modern authentication, and directory sync; Intune-based device management experience is a strong plus.
  • Ways of Working: Ability to collaborate directly with software engineers, scientists, and cross-functional stakeholders; strong communication skills to explain complex infrastructure concepts clearly; experience in biotech or research environments is helpful but not required if you’re excited about the domain.

Skills

  • Cloud architecture and engineering: AWS, Terraform, CloudFormation, automation-first workflows
  • Networking: routing, switching, firewalls, SD-WAN, VPNs, hybrid cloud connectivity
  • Identity and security: IAM, Conditional Access, Entra/Azure AD, endpoint management (Intune)
  • Observability and telemetry: CloudWatch, Grafana, telemetry pipelines, alerting
  • Scripting and automation: Python, Bash, or similar