Senior DMPK Director

Role: Senior Director of DMPK responsible for leading drug metabolism, pharmacokinetics, and modeling strategies to advance drug candidates from discovery through development and support regulatory submissions. Responsibilities include overseeing ADME characterization, developing in vitro to in vivo correlations, analyzing pharmacokinetic and pharmacodynamic data, and ensuring studies comply with regulatory guidance. The role involves close collaboration with Discovery, Clinical Pharmacology, CMC, Toxicology, and Regulatory teams to facilitate seamless molecule progression and regulatory document preparation. Qualifications: PhD in Pharmacokinetics, Drug Metabolism, Pharmaceutical Sciences, or related field; minimum 12 years of relevant industry experience; deep expertise in ADME studies, drug transporters, enzyme kinetics, and modeling techniques; extensive experience managing CROs, supporting IND/NDA submissions, and working on biologics such as antibody-drug conjugates is preferred. High-Value: leadership in DMPK for biopharma development, with a strong emphasis on translational ADME strategies, regulatory documentation, and collaboration across functions. Work setup: office-based with a modern, collaborative environment; travel requirements not specified but may include industry-standard levels.