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Senior Director, US Medical Affairs – Nephrology

Vertex Pharmaceuticals
18 days ago
Remote friendly (Boston, MA)
United States
Medical Affairs
General Summary:
The Senior Director (non-MD) serves as a US Medical Affairs asset lead responsible for strategic planning and execution of launch and lifecycle assets within the Vertex nephrology portfolio. Provides scientific leadership across cross-functional teams to align medical strategies with corporate objectives, patient needs, and the US treatment landscape. Builds and leads a team of Medical Directors and Associate Medical Directors while serving as a trusted scientific partner.

Key Duties & Responsibilities:
- Lead development, execution, and refinement of US Medical Affairs strategic/operational plan for assigned asset(s) from pre-launch through lifecycle.
- Serve as primary internal medical-scientific authority; interpret data and translate into actionable medical strategy.
- Build trusted relationships with US nephrology thought leaders, academic investigators, and external experts.
- Partner cross-functionally with Commercial, Market Access, HEOR, Regulatory, Clinical Development, and Corporate Communications for aligned launch readiness.
- Design and execute medical evidence generation initiatives (e.g., investigator-sponsored research, advisory boards, medical education).
- Deliver compliant, fair, balanced scientific presentations/communications.
- Provide medical input into promotional/non-promotional material review (CRC/MLR) to ensure substantiation and compliance.
- Establish and track medical KPIs; use scenario planning and market foresight.

Required Education:
- Terminal doctoral degree (PhD, PharmD, MD, DO, or equivalent).

Required Experience:
- 10+ years Medical Affairs/related scientific experience.
- 3+ years supervisory/people management.

Required Knowledge/Skills:
- US medical launch strategy experience.
- High EQ; relationship building internally/externally.
- Ability to deliver in a highly matrixed environment.
- Scientific knowledge of nephrology/immunology/related areas and evidence generation.
- Strong written/oral communication; influence senior leadership.
- Analyze complex data and translate to strategy; deliver high-impact projects on timelines.
- Proactive, organized; manage shifting pre-/launch priorities.

Other Requirements (Preferred):
- Prior launch experience in nephrology, immunology, or rare disease.
- Experience managing/developing Medical Directors/Associate Medical Directors.
- Nephrology-specific expertise preferred.

Pay Range:
- $252,000 - $378,000.

Application Instructions:
- Not specified in provided text.