Senior Director, US Medical Affairs - Head of Rheumatology

Role Summary

Senior Director, US Medical Affairs - Head of Rheumatology, based in Cambridge, MA. This leadership role within US Medical Affairs oversees zasocitinib rheumatology programs, accountable for medical strategy and ensuring TA- and product-specific strategies are developed and executed in collaboration with the Medical Unit. Serves as a subject matter expert on internal committees and with external experts, oversees data generation activities (including phase 4 studies), and contributes to medical unit insights and cross-functional communications.

Responsibilities

• Strategic responsibility for zasocitinib rheumatology Phase 4 programs
• TA and/or product focus may evolve to support organizational priorities; adapt as needed based on strategic direction
• Oversee and/or delegate execution of medical strategies by the medical unit in partnership with the PM to track progress against strategic plans, including development and communication of periodic reports
• Co-develop/coordinate US product medical strategy with medical unit; provide medical input into near-term and long-term strategic direction for assigned product/franchise
• Develop and update product-specific medical strategies in partnership with the medical unit, aligned with commercial brand strategy and global product teams
• Collaborate with VEG to develop evidence generation strategy
• Develop long-term lifecycle management strategy and tactics (HEOR, etc.)
• Maintain medical landscape and insights to inform strategy in collaboration with PM (as applicable)
• Leverage AI tools and data analytics to inform and support medical strategies, foster innovation, improve efficiencies, and aid decision-making
• Identify opportunities to leverage emerging AI technologies to improve patient care and healthcare landscape
• Serve as in-house medical and scientific expert for therapies within the assigned TA; represent medical affairs at internal and external meetings
• Generate insights and execute ad board strategies; synthesize insights for medical unit and cross-functional stakeholders; update medical landscape and strategy as appropriate
• Develop external KOL relationships and insights through advisory boards, professional associations, meetings, and conferences; manage global interactions with US KOLs
• Manage budgeting in partnership with PM or delegates and TA Head
• Partner with medical unit leads to ensure strategic alignment and execution of franchise/product medical strategy across tactics (grants, communications, publications, research, field medical, etc.); support medical review of materials
• Lead and coordinate with the medical unit; represent on SLT and cross-functional forums; provide input into confidential new business development
• Demonstrate leadership behaviors: strategic enterprise thinking, enabling environment, focus on priorities, elevate organizational capabilities, strong communication and influence, executive presence, and collaboration

Qualifications

• Advanced Doctoral Degree (e.g., MD, DO, PhD, PharmD)
• 12+ years of pharmaceutical industry experience; 7+ years of relevant clinical practice, research, or academic experience
• Experience with clinical research, publications, congress presentations, and public speaking
• Dermatology and/or rheumatology experience
• Proficiency in evaluating, adopting, and embedding AI-powered solutions and platforms within medical affairs
• Ability to leverage AI tools and data analytics to inform and guide medical strategies
• Commitment to ongoing education in emerging AI technologies and their implications for rheumatology care
• Commitment to high standards of data privacy, ethics, and regulatory compliance in applying AI within medical affairs
• Travel up to 30%, primarily domestic

Skills

• Strategic medical planning and execution
• Leadership and people management; cross-functional collaboration
• Communication and executive storytelling; stakeholder management
• Data analytics and use of AI to inform strategy
• Ad board design and insights synthesis
• External engagement with KOLs and professional networks
• Budgeting and resource management
• Medical communications, publications, and scientific review processes

Education

• Advanced Doctoral Degree (e.g., MD, DO, PhD, PharmD)

Additional Requirements

• Travel up to 30%, primarily domestic