Senior Director, US Finance Lead

Role Summary

Senior Director, US Finance Lead responsible for driving the US finance function to support argenx’s innovation mission. Oversees financial planning and analysis, optimizes the US P&L, and provides actionable insights to guide commercial and medical affairs strategy. Partners with cross-functional teams to advance the US portion of the company’s vision from discovery through commercialization, acting as a key business partner to accelerate growth and ensure alignment with global priorities.

Responsibilities

• Play a leadership role in finance to support argenx‚Äôs innovation mission in the US by ensuring the financial health, strategic allocation of resources, and sustainable growth of the US business
• Responsible for all aspects of financial planning and analysis, financial reporting, budget and forecasts preparation, focusing on value creation and aligning resources with strategic priorities
• Actively involved in launch plan projects, providing financial support to key functional areas critical to the launch plan
• Lead innovation by developing a state-of-the-art planning and management reporting process to forecast US financial results and deliver timely insights
• Prepare annual budgets and quarterly forecasts in partnership with HQ Finance, reporting variances and recommending actions
• Develop and maintain long-range planning (LRP) and a sales and operating model for multiple indications
• Lead monthly management accounts to enable real-time decisions and support real-time dashboards and AI-supported insights for the commercial business
• Develop and maintain inventory management for stable supply of all products to serve patients, including forecasting and reporting of US supply needs
• Drive the development and maintenance of complex financial models, including LRP for bookings, revenue, expenses, P&L, and cash flow management
• Partner with the Accounting team to support A/R, A/P, GL, analytical projects, and revenue recognition, ensuring accuracy and integrity of financial records
• Collaborate with the Controller and Internal Control Lead to review, update, and document business processes within the COSO framework, maintaining robust internal controls and SOX compliance
• Partner with the Head of Tax to ensure timely management of local, state, and federal reporting requirements, including tax filings and tax risk monitoring
• Serve as a key partner to cross-functional teams, driving the US innovation agenda from discovery through commercialization, and translating strategic vision into actionable results
• Lead and mentor a team of Financial Analysts, providing financial leadership and analytical support
• Execute special projects to drive operational efficiencies and business scaling while maintaining argenx culture and energy
• Demonstrate leadership attributes aligned with vision, servant leadership, the argenx Way, inclusivity, and a balance of hands-on operations with long-term strategic focus
• Bridge US operations with global ambitions by connecting financial strategy to the ‚Äúone company, one team, one plan‚Äù vision

Qualifications

• Extensive experience in finance business partnering supporting US biotech organizations
• Advanced degree in Accounting, Economics, or a related field
• Minimum of 10+ years of comprehensive accounting and finance experience, with significant time as Finance Director/Controller or equivalent
• Strong modeling, analytical, and critical thinking skills; detail-oriented and structured
• Excellent IT skills, including ERP systems (Oracle preferred) and Microsoft Office
• Proven ability to thrive under pressure and tight deadlines with an autonomous, hands-on work style
• Ability to scale thoughtfully while preserving energy and core culture
• Ability to connect financial strategy to global ambitions and align US operations with the broader company plan
• Curiosity, a commitment to learning, and a passion for serving patients

Education

• Advanced degree in Accounting, Economics, or a related field