The Senior Director, Trade & Channel Operations will build Amylyx’s U.S. distribution and channel model from the ground up in preparation for a future commercial launch.
Responsibilities:
- Design and build the U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launch
- Lead contracting strategy for specialty pharmacies and distributors (distribution/service agreements, fee schedules, data requirements, service levels)
- Integrate distribution channels with service programs and field initiatives for a seamless customer experience
- Collaborate with Supply Chain and Finance to support 3PL operations (order-to-cash, inventory, data exchange, shipping, returns, chargebacks)
- Establish and manage noncommercial and free-goods pharmacy operations
- Forecast and model channel performance; assess specialty pharmacy throughput to ensure timely, reliable patient access
- Develop distribution analytics (inventory visibility, service metrics, dispense data, time to therapy, partner scorecards); lead specialty pharmacy QBRs
- Partner cross-functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations for launch readiness
- Serve as a senior Market Access leader for launch planning, forecasting, patient access workflows, and distribution strategy
- Optimize post-launch distribution operations via root-cause remediation, vendor KPI management, and process improvements
Required Qualifications:
- Bachelor’s degree
- 12+ years of biopharmaceutical trade and distribution experience, including leadership of specialty pharmacy and distributor networks
- Prior U.S. product launch experience
- Experience designing/implementing channel strategies for product launches
- Ability to assess/manage/influence channel partner performance to contractual expectations
- Hands-on 3PL operations experience (serialization, state licensing, compliant distribution processes)
- Strength in contract negotiation, vendor management, and commercial channel operations
- Deep understanding of payer reimbursement, hub/patient support integration, channel economics, and order-to-cash workflows
- Proven people leadership; experience managing large pharmaceutical vendors
- Excellent communication, vendor management, analytical, and project execution capabilities
Compensation:
- Estimated pay range: $255,000 - $287,000 USD
Work Location/Conditions (as stated):
- Remote within the U.S.; not considering applicants from Alaska, Arizona, Hawaii, Michigan, and Tennessee
- Travel to Cambridge, MA several times per year
- Access to a suitable remote work setup (privacy, reliable internet, phone, video conferencing)
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