Senior Director, Toxicology

Role: Senior Director, Toxicology at a clinical-stage biopharma focusing on hematologic diseases, leading nonclinical safety assessments across all drug development phases. Responsibilities include designing and interpreting GLP toxicology, reproductive toxicology, carcinogenicity, and safety pharmacology studies; managing budgets and study timelines; overseeing GLP testing site visits; collaborating with cross-functional teams (clinical development, DMPK, discovery) for data interpretation and regulatory submissions. Requirements: D. in toxicology with 10-14 years of experience overseeing toxicology programs and GLP studies within pharma; strong knowledge of global guidelines (ICH, FDA, EMA); experience supporting IND-enabling and late-stage toxicity studies; proven skills in regulatory documentation and scientific communication; excellent collaboration abilities. Preferred: experience with both large and small molecules, hematology/rare disease drug development, D.A.B.T certification. HighValue: toxicology leadership, GLP study oversight, regulatory filing expertise, hematology focus, IND support, experience with regulatory agencies. WorkSetup: hybrid Watertown, MA; flexible work environment.