Senior Director, Strategic Portfolio Management Team Lead

Role Summary

Senior Director, Strategic Portfolio Team Lead. You’ll transform Pfizer’s digital portfolio management into a unified, streamlined engine for innovation, architecting standards, tools, and practices that empower portfolio leaders across Centers of Excellence and Creation Centers. You will serve as the enterprise architect and challenger for Pfizer’s digital investment agenda, ensuring initiatives align to the digital strategy and future vision, and you will influence the Digital & Technology Leadership Team to fund the vital initiatives and re-balance as priorities shift. Work location: Hybrid.

Responsibilities

• Enterprise Portfolio Strategy & Governance
• Set and govern the standards, methodologies, and tools for portfolio management across the enterprise, ensuring consistency, transparency, and strategic alignment.
• Lead cross-functional prioritization and value realization efforts, partnering with Digital & Technology LT and portfolio leads to optimize resource allocation and maximize business impact.
• Continuously assess the portfolio through rigorous reviews, surfacing start/stop/scale recommendations that keep investments aligned to Pfizer’s digital strategy.
• Innovation & Continuous Improvement
• Champion the integration of AI, advanced analytics, and best-in-class practices to modernize portfolio management and accelerate decision-making.
• Act as a change agent, driving continuous improvement and fostering a culture of innovation and accountability.
• Identify low-value work, bottlenecks, and duplication across portfolio processes; recommend simplification, standardization, and automation in partnership with Digital Process Reinvention Lead.
• Strategic Collaboration & Influence
• Collaborate with the Portfolio Value Storyteller and Reinvention team to ensure a unified, compelling narrative for digital investments and to reimagine portfolio processes.
• Influence senior management decisions, providing strategic recommendations that shape the direction of Pfizer’s digital transformation.
• Make actionable recommendations to Digital & Technology leaders on portfolio optimization.
• Center of Excellence Leadership
• Operate as the strategic leader of a Center of Excellence for portfolio management, ensuring that standards, insights, and innovations are shared and adopted across all business units.
• Leadership & Enablement
• Build, mentor, and empower a high-performing team (2–4 direct reports), cultivating a culture of innovation, accountability, and continuous learning.
• Mobilize matrixed resources and partnerships to deliver breakthrough results.
• Provide transparent insights, dashboards, and decision intelligence that enable senior leaders to act proactively and decisively.

Qualifications

• Required: A bachelor’s degree (digital technology preferred)
• Required: 12+ years in portfolio management, strategy, or program leadership roles
• Required: Proven experience developing and implementing enterprise-wide standards or tools
• Required: Demonstrated ability to lead cross-functional teams and influence at the executive level
• Required: Experience with digital transformation and AI-enabled portfolio practices
• Required: Recognized thought leader in digital transformation and portfolio management
• Required: Experience leading in large, matrixed organizations
• Required: Strong analytical skills and proficiency with portfolio management tools
• Required: Exceptional communication and stakeholder engagement capabilities

• Preferred: MBA or relevant advanced degree

Education

• Bachelor’s degree (digital technology preferred)
• MBA or relevant advanced degree (Preferred)

Additional Requirements

• Non-standard Work Schedule, Travel Or Environment: Our business is a 7x24x365 endeavor. This role may on occasion require physical or virtual participation on a weekend, holiday, or after normal business hours.