Senior Director, SOX Compliance

Role Summary

Senior Director, SOX Compliance responsible for leading Madrigal’s enterprise-wide Sarbanes-Oxley (SOX) program, updating the control environment, and supporting global expansion and public company responsibilities. Collaborates across functions to strengthen internal controls, mitigate risk, and ensure SOX 404 compliance while fostering a culture of operational excellence.

Responsibilities

• Maintain and enhance Madrigal‚Äôs SOX compliance program, including scoping, risk assessment, control design, documentation, testing, remediation, and ongoing monitoring.
• Partner with Finance, IT, Legal, HR, and business operations to ensure controls are properly designed and operating effectively across all key processes and systems.
• Lead the annual SOX risk assessment and control initiatives to ensure compliance efforts are efficient and aligned with business priorities.
• Lead annual internal and external process walkthroughs.
• Manage relationships with external auditors and consultants to ensure timely coordination of SOX testing and reporting.
• Drive continuous improvement of SOX-related processes, automation opportunities, and control environment maturity.
• Lead RFP and implementation process for SOX software.

Qualifications

• Bachelor‚Äôs degree in Accounting, Finance, or related field; CPA or CIA required.
• 15+ years of progressive experience in Finance with 5+ years in SOX compliance, internal controls, and risk management ‚Äî ideally including both public accounting and corporate experience in the biotech or pharmaceutical industry.
• Proven success building or transforming a SOX function within a complex, global organization.
• Deep knowledge of SOX 404 compliance, COSO frameworks, internal controls, and PCAOB standards.
• Strong understanding of IT general controls (ITGCs), automated controls, and system implementation risk.
• Exceptional communication and leadership skills with the ability to influence and align stakeholders across all levels of the organization.
• Demonstrated ability to build and mentor a high-performing team and effectively manage external partners.
• Willingness to travel up to ~10% (domestic and international).

Skills

• SOX 404 compliance
• COSO framework
• Internal controls evaluation and remediation
• IT general controls (ITGCs) and automated controls
• Relationship management with external auditors
• Effective communication to senior leadership and Audit Committee

Education

• Bachelor‚Äôs degree in Accounting, Finance, or related field; CPA or CIA required.