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Senior Director, Small Molecule Drug Discovery in Inflammation Discovery

Amgen
August 20, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Clinical Research and Development
Role: Senior Director leading early-stage small molecule drug discovery in inflammation at Amgen, overseeing target identification through preclinical and IND stages. Responsibilities include defining strategic approaches for small molecule modalities, managing cross-functional teams, guiding pipeline progression, fostering external innovation, and representing Inflammation Research in governance forums. Qualifications: Doctorate with 5+ years (or equivalent) in immunology discovery research, plus 5+ years people management experience; preferred PhD or MD with expertise in immunology, pharmacology, or related fields. High-Value: focus on inflammatory diseases, small molecule modalities including degraders and molecular glues, early discovery to IND/FIH stages, leadership in immunology or related therapeutic areas, and experience with target/hit identification, medicinal chemistry, and translational science. Collaboration with R&D functions, regulatory support, and external partners is integral. Work setup and travel specifics are not detailed.