Senior Director, RWE/Epi Scientist Internal Medicine - Migraine

Role Summary

The Senior Director Internal Medicine generates real-world evidence (RWE) and epidemiology (Epi) studies in support of US migraine strategies across the drug development process. The role requires subject matter expertise in RWE and epidemiology, alignment with Medical Evidence Generation (MEG) Asset Leads and endorsement in the Integrated Evidence Plan (IEP). Responsibilities include authoring and reviewing study protocols, reports, and presentations, with communications to internal stakeholders, regulatory authorities, and medical professionals. The role ensures high quality, timely RWE/Epi deliverables and partners with the RWE/Epi TA lead to drive innovation and process improvement.

Responsibilities

• Design, lead and execute RWE/Epi studies as part of cross-functional IEPs
• Provide SME and thought leadership to advance RWE/Epi for high value medicines
• Partner with TA RWE/Epi lead and MEG TA Leads to ensure strategic input to IEPs via Global Medical Affairs Teams
• Collaborate to establish and operationalize processes and systems to deliver RWE/Epi studies and other deliverables to execute on IEP plans
• Stakeholder management: build coalitions and partnerships across disciplines and geographies to optimize team performance
• Provide critical assessments to inform asset-specific development strategy and review epidemiological data and literature
• Prepare study reports and present/publish results at scientific conferences and in peer-reviewed journals
• Participate in RWE/Epi peer review of study protocols and study reports
• Provide SME on US RWD available at Pfizer, including differences between databases and applicable research questions
• Deep expertise in US RWD types (claims, EHR, registries, surveys, telehealth, etc.)
• Rapidly assess feasibility of answering research questions with available RWD
• Manage feasibility analyses for development of study concepts
• Develop study concepts, present to governance, and address concerns until approved
• Develop study protocols for approved concepts and ensure adherence to SOPs
• Supervise and mentor more junior team members
• Act as SME for observational and non-interventional study design in line with scientific principles and regulatory guidance

Qualifications

• Required: Advanced degree (PhD in Epidemiology, population health, outcomes research, or related) with 7+ years of relevant experience (at least 3 in pharma or in partnerships with pharma); or MPH or related Master’s with 10+ years of experience
• Required: Experience operating within large cross-functional matrices and collaborating with multiple partners
• Required: Strong technical, analytic, problem-solving, and communication skills
• Required: Experience directing analyses of real-world data
• Required: Hands-on experience executing non-interventional studies (NIS) from protocol design to results delivery
• Required: Knowledgeable of the external regulatory environment for RWE and awareness of developments in epidemiology, medicine, and technology (e.g., AI)
• Preferred: Ability to develop and implement strategic plans and influence senior leadership
• Preferred: Experience developing RWE for neurological conditions (e.g., pain, headache, migraine) and working with patient-reported outcomes not readily available in RWD
• Preferred: Leadership experience across diverse teams, coaching others, and driving business impact
• Preferred: Work location near a Pfizer site (within 50 miles) or remote candidate; relocation support possible for those farther away