Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), Across Therapeutic Areas

Role Summary

Senior Director leading Real-World Evidence (RWE) strategy across therapeutic areas for Johnson & Johnson Innovative Medicine. Drive regulatory-grade evidence generation, cross-functional collaborations, and external thought leadership to shape the RWE ecosystem. Partner with senior leaders across R&D and commercial to build an integrated, agile program that informs clinical development and regulatory decision-making while elevating scientific leadership.

Responsibilities

• Strategic Leadership & Ecosystem Building
• Define and execute the RWE initiatives across therapeutic areas, ensuring alignment with long-term organizational goals
• Lead cross-functional RWE committees and foster high-impact partnerships with internal and external stakeholders
• Shape and elevate the enterprise-wide RWE ecosystem through innovation, governance, and capability building
• Regulatory Policy & Scientific Influence
• Serve as a strategic advisor on regulatory-grade evidence generation and policy shaping
• Lead preparation and presentation of scientific data packages for regulatory submissions and agency interactions
• Represent J&J in external forums to influence RWE standards and regulatory expectations
• Scientific Leadership & Methodological Excellence
• Chair the Methodology Review Board (MRB) and oversee a portfolio of high-impact RWE projects
• Establish best practices for novel study designs and implementation
• Promote continuous learning and innovation in emerging RWE methodologies and technologies
• Develop frameworks and tools to scale evidence generation and accelerate delivery
• Champion a culture of scientific rigor, collaboration, and execution excellence

Qualifications

• Required: Ph.D. or Master’s in epidemiology, biostatistics, outcomes research, health policy, or related field
• Required: 10+ years of relevant experience in biopharma, RWE consulting, or healthcare industries
• Required: 7+ years of experience as a people manager
• Required: Proven expertise in data extraction, cleaning, and analysis; strong grasp of advanced statistical methods
• Required: Experience with diverse data sources (EHR, claims, registries, trial data, digital health)
• Required: Strong communication skills with the ability to engage both technical and non-technical stakeholders
• Required: Proven leadership and influencing capabilities, with a track record of inspiring teams and driving cross-functional alignment
• Required: Highly motivated and intellectually curious, with strong executional rigor
• Required: Proficiency in R, Python, or SQL
• Preferred: Expertise in regulatory-grade evidence generation and regulatory engagement
• Preferred: Strong leadership in cross-functional initiatives and ability to influence without authority
• Preferred: Subject matter expertise in Oncology, Immunology, Neuroscience
• Preferred: Experience in matrixed organizations and global stakeholder engagement

Skills

• Data analysis and statistical methods for real-world evidence
• Regulatory engagement and communicating with agencies
• Cross-functional leadership and stakeholder management
• Strategic planning and ecosystem development
• Proficiency in R, Python, SQL

Education

• Ph.D. or Master’s in epidemiology, biostatistics, outcomes research, health policy, or related field