Senior Director, Program Management
Dyne Therapeutics
August 09, 2026
On-site
Waltham, MA
Operations
Role Summary
- Senior Director, Program Management (PM) responsible for facilitating and driving execution across activities required for successful development of one or more molecules.
- Partners with the Program Team Leader (PTL) and functional subject matter experts to ensure detailed, risk-aware plans and to integrate them into a cohesive program plan; maintains agility to incorporate emerging data.
Primary Responsibilities
- Lead operations of one or more cross-functional teams (priorities, goal achievement, resourcing; maintain a collaborative, sustainable environment).
- Partner with PTL to identify short-, medium-, and long-term team priorities.
- Drive execution of program vision/strategy for bringing medicine to patients.
- Facilitate creation and maintenance of core program strategy documents (TPP, Clinical Development Plan, Regulatory Strategy, Supply Strategy).
- Ensure non-clinical, clinical, regulatory, and commercialization strategies align with TPP and program strategy.
- Optimize development/commercialization plan for quality, speed, and cost.
- Ensure timely, clear program decisions via governance forums and key stakeholders.
- Create/maintain detailed cross-functional plans and visual summaries to build accountability.
- Maintain communication with Program Team, senior leadership, and stakeholders on status, priorities, risks, and needs.
- Evolve Program Management discipline with Head of Program Management for a growing portfolio.
- Stay current on R&D developments in muscle diseases and oligonucleotide discovery/development.
- Foster collaboration, innovation, and continual improvement.
Education & Skills Requirements
- Bachelor’s degree in science/related field; advanced degree or MBA preferred.
- 15+ years relevant biotech/pharma experience with increasing responsibility in drug development.
- Required: late-stage clinical development and commercial-stage program experience.
- Preferred: neuromuscular disease experience.
- Exceptional communication; influence without authority; cross-functional teamwork.
- Proficient with Microsoft Office 365 and PM tools (e.g., Smartsheet).
- Proven data-driven decision-making, urgency, relationship-building, comfort with ambiguity; ability to lead without authority.
MA Pay Range
- $233,000 - $285,000 USD.
- Senior Director, Program Management (PM) responsible for facilitating and driving execution across activities required for successful development of one or more molecules.
- Partners with the Program Team Leader (PTL) and functional subject matter experts to ensure detailed, risk-aware plans and to integrate them into a cohesive program plan; maintains agility to incorporate emerging data.
Primary Responsibilities
- Lead operations of one or more cross-functional teams (priorities, goal achievement, resourcing; maintain a collaborative, sustainable environment).
- Partner with PTL to identify short-, medium-, and long-term team priorities.
- Drive execution of program vision/strategy for bringing medicine to patients.
- Facilitate creation and maintenance of core program strategy documents (TPP, Clinical Development Plan, Regulatory Strategy, Supply Strategy).
- Ensure non-clinical, clinical, regulatory, and commercialization strategies align with TPP and program strategy.
- Optimize development/commercialization plan for quality, speed, and cost.
- Ensure timely, clear program decisions via governance forums and key stakeholders.
- Create/maintain detailed cross-functional plans and visual summaries to build accountability.
- Maintain communication with Program Team, senior leadership, and stakeholders on status, priorities, risks, and needs.
- Evolve Program Management discipline with Head of Program Management for a growing portfolio.
- Stay current on R&D developments in muscle diseases and oligonucleotide discovery/development.
- Foster collaboration, innovation, and continual improvement.
Education & Skills Requirements
- Bachelor’s degree in science/related field; advanced degree or MBA preferred.
- 15+ years relevant biotech/pharma experience with increasing responsibility in drug development.
- Required: late-stage clinical development and commercial-stage program experience.
- Preferred: neuromuscular disease experience.
- Exceptional communication; influence without authority; cross-functional teamwork.
- Proficient with Microsoft Office 365 and PM tools (e.g., Smartsheet).
- Proven data-driven decision-making, urgency, relationship-building, comfort with ambiguity; ability to lead without authority.
MA Pay Range
- $233,000 - $285,000 USD.