Senior Director, Portfolio & Program Management
Vertex Pharmaceuticals
August 21, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Operations
Role: Senior Director, Portfolio & Program Management, leading cross-functional project excellence across drug development stages from research through commercialization. Responsibilities include strategic and operational leadership of multiple programs, overseeing project lifecycle activities, facilitating communication among senior stakeholders, identifying and resolving roadblocks, and optimizing processes through innovation. The role involves mentoring managers, managing project performance, and aligning portfolio strategies with corporate objectives. Requirements: Bachelor's in Life Sciences, 12+ years of experience with 5+ years in management; expertise in project/portfolio management, strategic planning, financial/resource management, and drug discovery/development across disciplines. High-Value: focus on biotech/pharma drug development, cross-functional leadership, portfolio oversight, and stakeholder collaboration; hybrid work model with flexibility. The position reports within a global biotech company, emphasizing leadership in a regulated environment, with a focus on ensuring program success throughout the drug development lifecycle.