Senior Director, Portfolio and Technology Strategy
Pfizer
10 days ago
Remote friendly (Chesterfield, MO)
United States
IT
Role Responsibilities:
- Lead portfolio operations across BRD, aligning development priorities, pilot capacity, resources, timelines, and execution risk.
- Design and implement metric-driven portfolio tracking systems; collaborate to schedule and prioritize non-GMP and GMP pilot plant projects.
- Serve as primary contact to the BTxPS Portfolio group, transferring new project/technology updates into BRD; coordinate initiations and progression with ARD/PhRD.
- Work with BRD LT to manage rep assignments, triage project issues, and facilitate strategic portfolio input.
- Provide portfolio oversight and communication of milestones, deliverables, and issues.
- Provide strategic/technical leadership for non-GMP pilot plants for scale-up, process characterization, and drug substance delivery.
- Oversee pilot plant readiness: equipment strategy, maintenance/turnaround, media/buffer support, and inventory management.
- Provide strategic leadership for BRD technology strategy; define and steward the BRD technology roadmap with Global Supply and Digital.
- Primary contact to the BTxPS Technology Council; track proposals and coordinate funding/investment decisions.
- Develop and implement work plans for new technology initiatives; mentor BRD staff.
- Coordinate BRD legal agreements/external partnerships (NDAs, CDAs, MTAs, collaborations).
- Ensure regulatory considerations are embedded early with Regulatory CMC colleagues.
Basic Qualifications:
- BS/MS in Chemical/Biochemical Engineering, Biology, or related field with 12+ years biopharma development/manufacturing experience; or PhD with 7+ years.
- Proven experience leading and managing direct reports.
- Extensive experience in process development, pilot-scale operations, and portfolio enablement for biologics/advanced therapeutics.
- Demonstrated leadership in complex, multi-disciplinary, multi-site matrix environments.
- Deep understanding of GLP/GMP, regulatory guidance, and CMC expectations.
- Ability to make strategic decisions balancing rigor, priorities, and speed.
Preferred Qualifications:
- Portfolio planning/governance/development operations for complex biologics pipeline.
- Advancing novel technologies into clinical programs.
- Cross-functional influence across Research, Manufacturing, Regulatory, and Digital.
- Experience transitioning programs to commercial manufacturing.
- Experience managing external collaborations/consortia/strategic partnerships.
Benefits/Compensation:
- Eligible for Global Performance Plan bonus target (25% of base) and share-based long-term incentive; comprehensive benefits including 401(k) with match, paid leave, and health coverage.
Application Instructions:
- Not specified in the provided text.
- Lead portfolio operations across BRD, aligning development priorities, pilot capacity, resources, timelines, and execution risk.
- Design and implement metric-driven portfolio tracking systems; collaborate to schedule and prioritize non-GMP and GMP pilot plant projects.
- Serve as primary contact to the BTxPS Portfolio group, transferring new project/technology updates into BRD; coordinate initiations and progression with ARD/PhRD.
- Work with BRD LT to manage rep assignments, triage project issues, and facilitate strategic portfolio input.
- Provide portfolio oversight and communication of milestones, deliverables, and issues.
- Provide strategic/technical leadership for non-GMP pilot plants for scale-up, process characterization, and drug substance delivery.
- Oversee pilot plant readiness: equipment strategy, maintenance/turnaround, media/buffer support, and inventory management.
- Provide strategic leadership for BRD technology strategy; define and steward the BRD technology roadmap with Global Supply and Digital.
- Primary contact to the BTxPS Technology Council; track proposals and coordinate funding/investment decisions.
- Develop and implement work plans for new technology initiatives; mentor BRD staff.
- Coordinate BRD legal agreements/external partnerships (NDAs, CDAs, MTAs, collaborations).
- Ensure regulatory considerations are embedded early with Regulatory CMC colleagues.
Basic Qualifications:
- BS/MS in Chemical/Biochemical Engineering, Biology, or related field with 12+ years biopharma development/manufacturing experience; or PhD with 7+ years.
- Proven experience leading and managing direct reports.
- Extensive experience in process development, pilot-scale operations, and portfolio enablement for biologics/advanced therapeutics.
- Demonstrated leadership in complex, multi-disciplinary, multi-site matrix environments.
- Deep understanding of GLP/GMP, regulatory guidance, and CMC expectations.
- Ability to make strategic decisions balancing rigor, priorities, and speed.
Preferred Qualifications:
- Portfolio planning/governance/development operations for complex biologics pipeline.
- Advancing novel technologies into clinical programs.
- Cross-functional influence across Research, Manufacturing, Regulatory, and Digital.
- Experience transitioning programs to commercial manufacturing.
- Experience managing external collaborations/consortia/strategic partnerships.
Benefits/Compensation:
- Eligible for Global Performance Plan bonus target (25% of base) and share-based long-term incentive; comprehensive benefits including 401(k) with match, paid leave, and health coverage.
Application Instructions:
- Not specified in the provided text.