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The Senior Director, Portfolio and Operations is a strategic leadership role within Pfizer Digital, responsible for driving portfolio governance, operational excellence, and business operations across the organization. This role ensures alignment of portfolio initiatives with enterprise priorities, optimizes resource utilization, and enables transparent decision-making. It oversees continuous improvement and communications for the R&D Creation Center and AI Center of Excellence, leads Digital-wide Operations Planning, and manages support for the Digital Capital Budget. Reporting to the VP, Strategic Initiatives and Delivery, the Senior Director leads the Portfolio and Operations team and provides horizontal leadership across all lines of business.