Senior Director, PM Portfolio Lead, Cell Therapy

Role Summary

Senior Director, PM Portfolio Lead, Cell Therapy. Provide line management leadership for up to 10 Program Management teammates, oversee program and project execution for a specific therapeutic area portfolio, and serve as a strategic partner to Global Franchise Leads and Therapeutic Area Heads. May act as interim Program Management Lead for an asset to shape and deliver the Target Product Profile (TPP) and Asset Development Plan (ADP).

Responsibilities

• Oversee a group of PMs assigned to asset programs and development projects of varying scope and complexity.
• Provide line management, coaching and development to grow within the PM team as subject matter experts.
• Prioritize time to oversee execution of the therapeutic area portfolio and personnel line management; may serve as interim PM Lead as needed.
• Partner with Global Franchise Leads and Therapeutic Area Heads; manage assignments and performance; oversee upcoming asset and portfolio inflection points; manage risk; contribute to disease area strategies; evolve the GPT Operating Model.
• Ensure team delivers PM responsibilities, including development and execution of ADP, schedules, critical path, risk management, governance readiness, PM systems and processes, budget and resource health, and data quality.
• Maintain oversight of key development inflection points; challenge ADPs and identify acceleration opportunities; coach team members for PM career growth; participate in PM Leadership Team activities; share best practices for transformational change.
• Build relationships with stakeholders across GDD and non-GDD functions to advance the portfolio; ensure PM outputs support governance and decision-making processes.
• Provide interim Program Management Lead support as needed, delivering ADP execution, integrated timelines, risk management, budgeting, governance preparation, and matrix management of PM resources.

Qualifications

• Advanced degree (MS/MBA or Ph.D. desirable). PMP certification desirable.
• At least 5 years of line management experience.
• 15+ years in the drug development space, including 10+ years in project/portfolio management or leadership of cross-functional matrix teams; proven success at Director level.
• Thorough knowledge of R&D and commercialization processes; understanding of disease areas and drug development pathways.
• Strong leadership, executive presence, and ability to influence without authority; excellent communication and stakeholder management skills.
• Experience mentoring others in core PM methodologies (project planning and control, risk management, stakeholder management).
• Excellent organizational and time management skills; ability to balance speed, quality, and cost; promote inclusion and psychological safety.

Skills

• Project/Portfolio management across multiple asset indications and phases.
• ADP/TPP development; integrated cross-functional timelines; scenario planning; risk management.
• Budgeting and resource planning; governance preparation; data quality and PM system adherence.
• Strong communication, presentation, and influencing skills; executive-level communication.
• Leadership and mentorship; capability to build high-performing teams; change leadership.

Education

• Advanced degree in Life Sciences or related field; PMP is desirable.

Additional Requirements

• Travel and on-site requirements as dictated by role; not specified in detail.