Senior Director, Oncology Pharmacology
Jazz Pharmaceuticals
August 23, 2026
Full-time
Remote friendly (Philadelphia, PA)
Worldwide
Clinical Research and Development
Role: Lead and manage the oncology pharmacology team from discovery through regulatory approval, overseeing preclinical efficacy, mechanism of action, and biomarker studies across multiple therapeutic modalities. Responsibilities: design and execute experiments, review and contribute to regulatory documents, collaborate with cross-functional teams including Clinical Development, Toxicology, and Biomarkers; serve as a program lead and mentor junior scientists. Requirements: Ph.D. in biology, biochemistry, immunology, pharmacology, or related field; extensive industry experience in oncology drug development, particularly immuno-oncology, with familiarity across small molecules, biologics, ADCs, cell and gene therapies; proven leadership in early oncology programs, managing CROs, and authoring IND/NDA submissions. HighValue: oncology (solid tumors, hematologic malignancies), immuno-oncology, multiple modalities (small molecules, biologics, cell therapies), nonclinical to regulatory stages, cross-functional leadership, and experience in immunological endpoints. WorkSetup: not specified.