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Senior Director, Oncology Pharmacology

Jazz Pharmaceuticals
August 23, 2026
Full-time
Remote friendly (California, United States)
Worldwide
Clinical Research and Development
Role: Lead oncology pharmacology scientific team from discovery through regulatory approval, managing both team and program responsibilities. Responsibilities: establish efficacy in disease models, demonstrate differentiation, elucidate mechanisms of action, identify biomarkers, support research and development, design and review experimental protocols, author technical and regulatory documents, collaborate cross-functionally with Clinical Development, Bioanalytical, Toxicology, and Regulatory teams, and mentor junior scientists. Requirements: Ph.D. in biology, biochemistry, immunology, pharmacology, or related discipline; extensive industry experience evaluating drug candidates in oncology, with expertise in immuno-oncology, diverse modalities (small molecules, biologics, cell/gene therapies), and nonclinical modeling. Preferred: leadership experience in early oncology programs, strong project management skills, and familiarity with regulatory submissions (IND/NDA/BLA). HighValue: oncology, immuno-oncology, multiple modalities, nonclinical efficacy and biomarker development, IND/ NDA/ BLA experience, leadership in matrix environments. WorkSetup: not specified; likely hybrid or onsite based on industry standards.