Senior Director of Clinical Science - Lung
Merck
August 19, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
Senior Director, Clinical Science – Lung
Responsibilities:
- Provide strategic Clinical Science leadership across lung disease area (multiple studies/programs/assets).
- Contribute to disease area strategy with input on development opportunities, scientific considerations, portfolio risks, and emerging data.
- Apply lung cancer expertise to guide study planning, data interpretation, and issue resolution; integrate insights across studies/assets.
- Standardize Clinical Science approaches (medical data review practices, data interpretation principles, key deliverables) and align scientific approaches across the portfolio.
- Provide senior scientific guidance for protocol development/amendments, study design, endpoints, eligibility, and biomarker strategy; serve as lung subject matter resource.
- Contribute to portfolio governance and senior leadership reviews.
- Lead and develop Clinical Science talent (may manage Directors/Principal Scientists/Clinical Scientists).
- Ensure compliance with regulatory requirements, company policies, and procedures; support inspection readiness.
- Partner with Clinical Operations, Regulatory Affairs, Biostatistics/Data Management, Drug Safety/Pharmacovigilance, Translational Medicine, Medical Affairs, and others.
Qualifications:
- Advanced degree (PhD or PharmD) + at least 7 years lung oncology drug development experience; OR Master’s in life sciences + 12 years.
- Significant clinical development/clinical science/oncology development experience in pharma/biotech; demonstrated Clinical Science leadership across studies/programs/assets.
- Strong lung cancer disease biology and treatment landscape knowledge; clinical trial design and oncology data review/interpretation experience.
Required Skills:
Change agility; Clinical Development; Clinical Oncology; Clinical Reporting; Clinical Research; Clinical Sciences; Clinical Study/Trial Management; Medical Sciences; Oncology; People Leadership.
Benefits (if applicable): Annual bonus and long-term incentive; medical/dental/vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days.
Application instructions: Apply via https://jobs.merck.com/us/en (deadline listed on posting). Travel: 0–25%.
Responsibilities:
- Provide strategic Clinical Science leadership across lung disease area (multiple studies/programs/assets).
- Contribute to disease area strategy with input on development opportunities, scientific considerations, portfolio risks, and emerging data.
- Apply lung cancer expertise to guide study planning, data interpretation, and issue resolution; integrate insights across studies/assets.
- Standardize Clinical Science approaches (medical data review practices, data interpretation principles, key deliverables) and align scientific approaches across the portfolio.
- Provide senior scientific guidance for protocol development/amendments, study design, endpoints, eligibility, and biomarker strategy; serve as lung subject matter resource.
- Contribute to portfolio governance and senior leadership reviews.
- Lead and develop Clinical Science talent (may manage Directors/Principal Scientists/Clinical Scientists).
- Ensure compliance with regulatory requirements, company policies, and procedures; support inspection readiness.
- Partner with Clinical Operations, Regulatory Affairs, Biostatistics/Data Management, Drug Safety/Pharmacovigilance, Translational Medicine, Medical Affairs, and others.
Qualifications:
- Advanced degree (PhD or PharmD) + at least 7 years lung oncology drug development experience; OR Master’s in life sciences + 12 years.
- Significant clinical development/clinical science/oncology development experience in pharma/biotech; demonstrated Clinical Science leadership across studies/programs/assets.
- Strong lung cancer disease biology and treatment landscape knowledge; clinical trial design and oncology data review/interpretation experience.
Required Skills:
Change agility; Clinical Development; Clinical Oncology; Clinical Reporting; Clinical Research; Clinical Sciences; Clinical Study/Trial Management; Medical Sciences; Oncology; People Leadership.
Benefits (if applicable): Annual bonus and long-term incentive; medical/dental/vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days.
Application instructions: Apply via https://jobs.merck.com/us/en (deadline listed on posting). Travel: 0–25%.