Senior Director of Clinical Science - Lung
Merck
August 19, 2026
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Responsibilities
- Provide strategic Clinical Science leadership for lung disease across multiple studies, programs, and assets.
- Contribute Clinical Science input to disease area strategy (development opportunities, portfolio risks, implications of emerging data).
- Partner cross-functionally to align study planning, data interpretation, issue resolution, and development decisions.
- Standardize Clinical Science approaches (medical data review practices, interpretation principles, deliverables) while supporting program needs.
- Lead scientific guidance across studies/programs; interpret clinical data to assess trends, opportunities, risks, and implications.
- Contribute to protocol development/amendments, study design, endpoint selection, eligibility, and biomarker strategy.
- Present insights for governance/portfolio reviews and translate priorities into Clinical Science strategies/capabilities/resource plans.
- Manage and develop Directors/Principal Scientists/Clinical Scientists (as appropriate) and build talent.
- Ensure compliance with applicable regulatory requirements/policies and support inspection readiness.
Qualifications (Education/Experience)
- Required: PhD or PharmD + 7+ years lung oncology drug development OR Master’s in life sciences + 12+ years lung oncology drug development.
- Significant experience in Clinical Development/Clinical Science/oncology development (pharma/biotech).
- Deep lung cancer expertise (disease biology, treatment landscape, clinically meaningful endpoints).
- Strong oncology clinical trial design and clinical data review/interpretation.
Travel: 0–25%
Required Skills
- Change agility; Clinical Development; Clinical Oncology; Clinical Reporting; Clinical Research; Clinical Sciences; Clinical Study/Trial Management; Medical Sciences; Oncology; People Leadership.
Benefits (if applicable)
- Annual bonus and long-term incentive (if applicable); comprehensive health/retirement/paid time off benefits.
Application
- Apply via https://jobs.merck.com/us/en (deadline stated on posting).
- Provide strategic Clinical Science leadership for lung disease across multiple studies, programs, and assets.
- Contribute Clinical Science input to disease area strategy (development opportunities, portfolio risks, implications of emerging data).
- Partner cross-functionally to align study planning, data interpretation, issue resolution, and development decisions.
- Standardize Clinical Science approaches (medical data review practices, interpretation principles, deliverables) while supporting program needs.
- Lead scientific guidance across studies/programs; interpret clinical data to assess trends, opportunities, risks, and implications.
- Contribute to protocol development/amendments, study design, endpoint selection, eligibility, and biomarker strategy.
- Present insights for governance/portfolio reviews and translate priorities into Clinical Science strategies/capabilities/resource plans.
- Manage and develop Directors/Principal Scientists/Clinical Scientists (as appropriate) and build talent.
- Ensure compliance with applicable regulatory requirements/policies and support inspection readiness.
Qualifications (Education/Experience)
- Required: PhD or PharmD + 7+ years lung oncology drug development OR Master’s in life sciences + 12+ years lung oncology drug development.
- Significant experience in Clinical Development/Clinical Science/oncology development (pharma/biotech).
- Deep lung cancer expertise (disease biology, treatment landscape, clinically meaningful endpoints).
- Strong oncology clinical trial design and clinical data review/interpretation.
Travel: 0–25%
Required Skills
- Change agility; Clinical Development; Clinical Oncology; Clinical Reporting; Clinical Research; Clinical Sciences; Clinical Study/Trial Management; Medical Sciences; Oncology; People Leadership.
Benefits (if applicable)
- Annual bonus and long-term incentive (if applicable); comprehensive health/retirement/paid time off benefits.
Application
- Apply via https://jobs.merck.com/us/en (deadline stated on posting).