Senior Director of Clinical Science - Hematology
Merck
August 19, 2026
Remote friendly (Upper Gwynedd, PA)
United States
Clinical Research and Development
Responsibilities
- Provide strategic Clinical Science leadership across the hematology disease area (multiple studies, programs, and assets).
- Contribute to disease area strategy using hematologic oncology expertise to guide development opportunities, portfolio risks, and implications of internal/external data.
- Standardize Clinical Science approaches (medical data review practices, data interpretation, deliverables) and promote scientific consistency across studies while allowing program-specific needs.
- Provide senior scientific guidance: interpret clinical data across studies/cohorts/assets; frame key clinical/scientific/data issues for governance; contribute to protocol development/amendments, study design, endpoint selection, eligibility, and biomarker strategy.
- Contribute to governance and portfolio discussions with cross-study insights; translate portfolio priorities into Clinical Science strategies/capabilities/resource plans.
- Lead and develop Clinical Science talent (direct management as appropriate); coach/mentor and foster accountability and continuous learning.
- Collaborate cross-functionally (Clinical Ops, Regulatory, Biostatistics/Data Mgmt, Safety/PV, Translational Medicine, Medical Affairs) to ensure aligned planning and decision-making.
Qualifications
- PhD/PharmD + at least 7 years hematological oncology drug development, OR Master’s in life sciences + 12 years.
- Significant experience in Clinical Development/Clinical Science/oncology development (or related pharma/biotech function).
- Demonstrated Clinical Science leadership across multiple studies/programs/assets; deep hematologic cancer expertise; strong clinical trial design and oncology data review/interpretation; experience with cross-functional matrix teams.
Required Skills
- Change Agility; Clinical Development; Clinical Oncology; Clinical Reporting/Research/Sciences; Clinical Study & Trial Management; Hematology; Medical Sciences; Oncology; People Leadership; Scientific Literacy.
Benefits
- Eligible for annual bonus and long-term incentive (if applicable) and comprehensive benefits (medical/dental/vision, retirement/401(k), paid holidays, vacation, sick/compassionate days).
Application
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub if a current employee).
- Provide strategic Clinical Science leadership across the hematology disease area (multiple studies, programs, and assets).
- Contribute to disease area strategy using hematologic oncology expertise to guide development opportunities, portfolio risks, and implications of internal/external data.
- Standardize Clinical Science approaches (medical data review practices, data interpretation, deliverables) and promote scientific consistency across studies while allowing program-specific needs.
- Provide senior scientific guidance: interpret clinical data across studies/cohorts/assets; frame key clinical/scientific/data issues for governance; contribute to protocol development/amendments, study design, endpoint selection, eligibility, and biomarker strategy.
- Contribute to governance and portfolio discussions with cross-study insights; translate portfolio priorities into Clinical Science strategies/capabilities/resource plans.
- Lead and develop Clinical Science talent (direct management as appropriate); coach/mentor and foster accountability and continuous learning.
- Collaborate cross-functionally (Clinical Ops, Regulatory, Biostatistics/Data Mgmt, Safety/PV, Translational Medicine, Medical Affairs) to ensure aligned planning and decision-making.
Qualifications
- PhD/PharmD + at least 7 years hematological oncology drug development, OR Master’s in life sciences + 12 years.
- Significant experience in Clinical Development/Clinical Science/oncology development (or related pharma/biotech function).
- Demonstrated Clinical Science leadership across multiple studies/programs/assets; deep hematologic cancer expertise; strong clinical trial design and oncology data review/interpretation; experience with cross-functional matrix teams.
Required Skills
- Change Agility; Clinical Development; Clinical Oncology; Clinical Reporting/Research/Sciences; Clinical Study & Trial Management; Hematology; Medical Sciences; Oncology; People Leadership; Scientific Literacy.
Benefits
- Eligible for annual bonus and long-term incentive (if applicable) and comprehensive benefits (medical/dental/vision, retirement/401(k), paid holidays, vacation, sick/compassionate days).
Application
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub if a current employee).