Senior Director of Clinical Science - Hematology
Merck
August 19, 2026
Remote friendly (South San Francisco, CA)
United States
Clinical Research and Development
Responsibilities:
- Provide strategic Clinical Science leadership across hematology (multiple studies, programs, assets) and contribute to disease area strategy using expertise in hematologic cancers, disease biology, and clinically meaningful endpoints.
- Standardize Clinical Science approaches (medical data review practices, data interpretation principles, deliverables) and align scientific standards across studies while allowing program-specific needs; integrate cross-study/asset insights.
- Provide senior scientific guidance on clinical data interpretation, issue framing for governance, and support protocol development/amendments (design, endpoints, eligibility, biomarker strategy).
- Contribute to portfolio/governance reviews and senior leadership communications with sound scientific judgment.
- Lead people (Directors/Scientists as appropriate) via coaching, mentoring, and clear expectations in a matrix environment.
- Collaborate with cross-functional partners (Clinical Ops, Regulatory, Biostats/Data Mgmt, Drug Safety/PV, Translational Med, Medical Affairs) and represent Clinical Science in strategic decision forums.
- Ensure activities meet applicable regulatory requirements and support inspection readiness.
Qualifications (Education/Experience):
- PhD or PharmD + 7+ years hematological oncology drug development, OR Master’s in life sciences + 12+ years.
- Significant oncology clinical development/science experience; demonstrated cross-study Clinical Science leadership; strong oncology trial design/data review and interpretation; matrix cross-functional collaboration; people leadership.
Required skills:
Change agility; Clinical development/science/onco; clinical reporting/research/study & trial management; Hematology; Medical sciences; Oncology; People leadership; Scientific literacy.
Preferred skills:
- Current employees/contingent workers apply via “HERE”.
Benefits:
- Eligible for annual bonus/long-term incentive (if applicable); comprehensive benefits including medical/dental/vision, retirement (401k), paid holidays/vacation, compassionate and sick days.
Application instructions:
- Apply at https://jobs.merck.com/us/en (deadline listed on posting); job posting effective until 11:59:59PM day before 09/10/2026; Requisition ID: R413310.
- Provide strategic Clinical Science leadership across hematology (multiple studies, programs, assets) and contribute to disease area strategy using expertise in hematologic cancers, disease biology, and clinically meaningful endpoints.
- Standardize Clinical Science approaches (medical data review practices, data interpretation principles, deliverables) and align scientific standards across studies while allowing program-specific needs; integrate cross-study/asset insights.
- Provide senior scientific guidance on clinical data interpretation, issue framing for governance, and support protocol development/amendments (design, endpoints, eligibility, biomarker strategy).
- Contribute to portfolio/governance reviews and senior leadership communications with sound scientific judgment.
- Lead people (Directors/Scientists as appropriate) via coaching, mentoring, and clear expectations in a matrix environment.
- Collaborate with cross-functional partners (Clinical Ops, Regulatory, Biostats/Data Mgmt, Drug Safety/PV, Translational Med, Medical Affairs) and represent Clinical Science in strategic decision forums.
- Ensure activities meet applicable regulatory requirements and support inspection readiness.
Qualifications (Education/Experience):
- PhD or PharmD + 7+ years hematological oncology drug development, OR Master’s in life sciences + 12+ years.
- Significant oncology clinical development/science experience; demonstrated cross-study Clinical Science leadership; strong oncology trial design/data review and interpretation; matrix cross-functional collaboration; people leadership.
Required skills:
Change agility; Clinical development/science/onco; clinical reporting/research/study & trial management; Hematology; Medical sciences; Oncology; People leadership; Scientific literacy.
Preferred skills:
- Current employees/contingent workers apply via “HERE”.
Benefits:
- Eligible for annual bonus/long-term incentive (if applicable); comprehensive benefits including medical/dental/vision, retirement (401k), paid holidays/vacation, compassionate and sick days.
Application instructions:
- Apply at https://jobs.merck.com/us/en (deadline listed on posting); job posting effective until 11:59:59PM day before 09/10/2026; Requisition ID: R413310.