Senior Director of Clinical Science - Hematology
Merck
August 19, 2026
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Senior Director, Clinical Science – Hematology
Key Responsibilities
- Provide strategic Clinical Science leadership across the hematology disease area (multiple studies, programs, assets).
- Contribute to disease area strategy by advising on development opportunities, scientific considerations, portfolio risks, and implications of emerging internal/external data.
- Partner with Section Heads, Asset Leads, and Program Development leads to align Clinical Science activities with program/disease area objectives.
- Apply expertise in hematologic cancers (disease biology, treatment landscape, clinically meaningful endpoints) to inform study planning, data interpretation, and issue resolution.
- Standardize Clinical Science approaches (medical data review practices, interpretation principles, deliverables) and maintain portfolio standards/leading practices.
- Provide senior scientific guidance across studies/programs; interpret clinical data to identify trends, opportunities/risks, and program implications.
- Contribute to protocol development/amendments (study design, endpoint selection, eligibility, biomarker strategy) and serve as a hematology subject matter resource.
- Support governance/portfolio discussions and translate portfolio priorities into Clinical Science strategies, capabilities, and resource plans.
- Provide people leadership for scientific staff; coach/mentor and foster accountability, inclusion, and continuous learning.
- Collaborate with Clinical Operations, Regulatory Affairs, Biostatistics/Data Management, Drug Safety/Pharmacovigilance, Translational Medicine, Medical Affairs.
Compliance & Continuous Improvement
- Ensure activities follow applicable regulatory requirements, company policies, and established procedures; maintain inspection readiness as applicable.
- Identify opportunities to improve quality, consistency, and effectiveness; stay current on hematologic cancer developments.
Education/Experience
- PhD or PharmD + 7+ years hematological oncology drug development, OR Master’s in life sciences + 12+ years.
- Significant clinical development/science experience in pharma/biotech; demonstrated leadership across multiple studies/programs/assets.
Required Skills
Change agility; Clinical Development; Clinical Oncology; Clinical Reporting/Research/Sciences; Clinical Study/Trial Management; Hematology; Medical Sciences; Oncology; People Leadership; Scientific Literacy.
Travel
0–25%.
Application Instructions
Apply via https://jobs.merck.com/us/en (deadline stated on posting).
Key Responsibilities
- Provide strategic Clinical Science leadership across the hematology disease area (multiple studies, programs, assets).
- Contribute to disease area strategy by advising on development opportunities, scientific considerations, portfolio risks, and implications of emerging internal/external data.
- Partner with Section Heads, Asset Leads, and Program Development leads to align Clinical Science activities with program/disease area objectives.
- Apply expertise in hematologic cancers (disease biology, treatment landscape, clinically meaningful endpoints) to inform study planning, data interpretation, and issue resolution.
- Standardize Clinical Science approaches (medical data review practices, interpretation principles, deliverables) and maintain portfolio standards/leading practices.
- Provide senior scientific guidance across studies/programs; interpret clinical data to identify trends, opportunities/risks, and program implications.
- Contribute to protocol development/amendments (study design, endpoint selection, eligibility, biomarker strategy) and serve as a hematology subject matter resource.
- Support governance/portfolio discussions and translate portfolio priorities into Clinical Science strategies, capabilities, and resource plans.
- Provide people leadership for scientific staff; coach/mentor and foster accountability, inclusion, and continuous learning.
- Collaborate with Clinical Operations, Regulatory Affairs, Biostatistics/Data Management, Drug Safety/Pharmacovigilance, Translational Medicine, Medical Affairs.
Compliance & Continuous Improvement
- Ensure activities follow applicable regulatory requirements, company policies, and established procedures; maintain inspection readiness as applicable.
- Identify opportunities to improve quality, consistency, and effectiveness; stay current on hematologic cancer developments.
Education/Experience
- PhD or PharmD + 7+ years hematological oncology drug development, OR Master’s in life sciences + 12+ years.
- Significant clinical development/science experience in pharma/biotech; demonstrated leadership across multiple studies/programs/assets.
Required Skills
Change agility; Clinical Development; Clinical Oncology; Clinical Reporting/Research/Sciences; Clinical Study/Trial Management; Hematology; Medical Sciences; Oncology; People Leadership; Scientific Literacy.
Travel
0–25%.
Application Instructions
Apply via https://jobs.merck.com/us/en (deadline stated on posting).